Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 2/20 | 0.37 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.36 |
| ▸ | LIMK1 | P53667 | 1/20 | 0.36 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.36 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | IMPDH2 | P12268 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21769874 | 0.92 | MAPT (0.38) | KMT2AALDH1A1KDM4EMEN1NPC1 | |
| SCHEMBL17923455 | 0.90 | MAPT (0.37) | KMT2AALDH1A1KDM4EMEN1NPC1 | |
| SCHEMBL21769730 | 0.89 | HDAC1 (0.42) | KMT2AALDH1A1KDM4EMEN1NPC1 | |
| SCHEMBL21769573 | 0.88 | POLB (0.39) | KMT2AALDH1A1MEN1NPC1MAPT | |
| SCHEMBL17923449 | 0.88 | SMN1; SMN2 (0.36) | KMT2AALDH1A1KDM4EMEN1NPC1 | |
| SCHEMBL3892309 | 0.87 | NPC1 (0.37) | KMT2AKDM4EMEN1NPC1MAPT | |
| SCHEMBL21769885 | 0.87 | POLB (0.37) | ALDH1A1KDM4ENPC1MAPTHPGD | |
| SCHEMBL21769854 | 0.87 | KMT2A (0.39) | KMT2AALDH1A1KDM4EMEN1NPC1 | |
| SCHEMBL21769740 | 0.87 | L3MBTL1 (0.33) | KMT2AALDH1A1KDM4EMEN1MAPT | |
| SCHEMBL17923453 | 0.87 | MAPT (0.35) | KMT2AALDH1A1MEN1MAPTTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020038812-A1 | NEW PROCESS FOR THE PREPARATION OF AMENAMEVIR | RIJKSUNIVERSITEIT GRONINGEN (NL) | 2020-02-27 | — | — | WO | disclosed |