Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGDS | O60760 | 1/20 | 0.49 |
| ▸ | MAPK14 | Q16539 | 4/20 | 0.47 |
| ▸ | LCK | P06239 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.41 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | BRD4 | O60885 | 1/20 | 0.39 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.39 |
| ▸ | AHR | P35869 | 1/20 | 0.38 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.38 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 3/20 | 0.38 |
| ▸ | RAB9A | P51151 | 3/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3892753 | 0.82 | HPGDS (0.49) | HPGDSMAPK14LCKKMT2AALDH1A1 | |
| SCHEMBL7253124 | 0.81 | HPGDS (0.39) | HPGDSMAPK14LCKKMT2AMAPK8 | |
| SCHEMBL3767339 | 0.80 | RAB9A (0.51) | HPGDSMAPK14LCKKMT2AALDH1A1 | |
| SCHEMBL4035180 | 0.79 | MAPK14 (0.56) | HPGDSMAPK14LCKKMT2AALDH1A1 | |
| SCHEMBL396727 | 0.78 | POLB (0.53) | HPGDSMAPK14KMT2AMAPK8MAPK10 | |
| SCHEMBL2214850 | 0.76 | MAPK14 (0.46) | HPGDSMAPK14LCKKMT2AALDH1A1 | |
| SCHEMBL13213725 | 0.76 | POLB (0.50) | HPGDSMAPK14LCKKMT2ASMN1; SMN2 | |
| SCHEMBL3268236 | 0.76 | KMT2A (0.57) | HPGDSMAPK14KMT2AALDH1A1SMN1; SMN2 | |
| SCHEMBL14161063 | 0.75 | MAPK14 (0.43) | HPGDSMAPK14LCKKMT2AMAPK8 | |
| SCHEMBL3893646 | 0.75 | ALDH1A1 (0.43) | KMT2AALDH1A1SMN1; SMN2POLBNTRK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7511034-B2 | Dialkylhydroxybenzoic acid derivatives containing metal chelating groups and their therapeutic uses | SAMSUNG ELECTRONICS CO., LTD. (KR) | 2009-03-31 | — | — | US | claimed |
| US-7229988-B2 | Dialkylhydroxybenzoic acid derivatives containing metal chelating groups and their therapeutic uses | SAMSUNG ELECTRONICS CO., LTD. (KR) | 2007-06-12 | — | — | US | claimed |
| US-20060116377-A1 | Dialkylhydroxybenzoic acid derivatives containing metal chelating groups and their therapeutic uses | OH EU-GENE | 2006-06-01 | — | — | US | claimed |
| US-7511034-B2 | Dialkylhydroxybenzoic acid derivatives containing metal chelating groups and their therapeutic uses | SAMSUNG ELECTRONICS CO., LTD. (KR) | 2009-03-31 | — | — | US | disclosed |
| US-7229988-B2 | Dialkylhydroxybenzoic acid derivatives containing metal chelating groups and their therapeutic uses | SAMSUNG ELECTRONICS CO., LTD. (KR) | 2007-06-12 | — | — | US | disclosed |
| US-20060116377-A1 | Dialkylhydroxybenzoic acid derivatives containing metal chelating groups and their therapeutic uses | OH EU-GENE | 2006-06-01 | — | — | US | disclosed |
| US-20040214827-A1 | Dialkylhydroxybenzoic acid derivatives containing metal chelating groups and their therapeutic uses | SAM-SUNG ELECTRONICS CO., LTD. (KR) | 2004-10-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060116377-A1 | Dialkylhydroxybenzoic acid derivatives containing metal chelating groups and their therapeutic uses | SOD1, DDO, LPO | HPGDS 712/4885MAPK14 1651/4885LCK 2000/4885 |
| US-20040214827-A1 | Dialkylhydroxybenzoic acid derivatives containing metal chelating groups and their therapeutic uses | SOD1, DDO, LPO | HPGDS 851/4885MAPK14 1843/4885LCK 1923/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.