Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV4 | Q9HBA0 | 1/20 | 0.54 |
| ▸ | HTR2A | P28223 | 1/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.39 |
| ▸ | GRM5 | P41594 | 1/20 | 0.39 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.38 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.38 |
| ▸ | AGPAT2 | O15120 | 2/20 | 0.38 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.37 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.37 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.37 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.37 |
| ▸ | DRD4 | P21917 | 1/20 | 0.37 |
| ▸ | PDE5A | O76074 | 1/20 | 0.36 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | AR | P10275 | 3/20 | 0.36 |
| ▸ | NR3C2 | P08235 | 2/20 | 0.35 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.35 |
| ▸ | PGR | P06401 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6476469 | 0.83 | TRPV4 (0.54) | TRPV4HTR2AKCNH2GRM5S1PR1 | |
| SCHEMBL14468631 | 0.83 | TRPV4 (0.54) | TRPV4HTR2AKCNH2GRM5S1PR1 | |
| SCHEMBL411153 | 0.83 | AR (0.47) | TRPV4HTR2AKCNH2GAAAR | |
| Hydrochloric Acid SCHEMBL6476582 | 0.82 | TRPV4 (0.52) | TRPV4HTR2AKCNH2GRM5S1PR1 | |
| SCHEMBL8735777 | 0.81 | TRPV4 (0.51) | TRPV4HTR2AKCNH2GRM5S1PR1 | |
| SCHEMBL27001729 | 0.81 | CYP19A1 (0.41) | TRPV4HTR2AKCNH2ARALDH1A1 | |
| SCHEMBL1664918 | 0.81 | TRPV4 (0.51) | TRPV4HTR2AKCNH2GRM5S1PR1 | |
| SCHEMBL1402437 | 0.80 | TRPV4 (0.61) | TRPV4GRM5S1PR1GABRG2GABRB3 | |
| SCHEMBL5900831 | 0.80 | KCNH2 (0.42) | TRPV4HTR2AKCNH2S1PR1AR | |
| SCHEMBL14468537 | 0.80 | TRPV4 (0.54) | TRPV4HTR2AKCNH2GRM5S1PR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7241625-B2 | Carbonyl compound scavenger and method of quantifying carbonyl compound using the same | SUMIKA CHEMICAL ANALYSIS SERVICE, LIMITED (JP) | 2007-07-10 | — | — | US | disclosed |
| US-7241625-B2 | Carbonyl compound scavenger and method of quantifying carbonyl compound using the same | SUMIKA CHEMICAL ANALYSIS SERVICE, LIMITED (JP) | 2007-07-10 | — | — | US | disclosed |
| US-20060275913-A1 | Carbonyl compound scavenger and method of quantifying carbonyl compound using the same | SUMIKA CHEMICAL ANALYSIS SERVICE, LIMITED (JP) | 2006-12-07 | — | — | US | disclosed |
| US-6900319-B2 | Thrombin inhibitors | ABBOTT GMBH & CO. KG (DE) | 2005-05-31 | — | — | US | disclosed |
| US-20020169318-A1 | Novel thrombin inhibitors | ABBVIE DEUTSCHLAND GMBH & CO KG (DE) | 2002-11-14 | — | — | US | disclosed |
| US-6444817-B1 | ANTICOAGULANTS | ABBOTT LABORATORIES | 2002-09-03 | — | — | US | disclosed |
| US-6030972-A | 2- OR 5-AMINOMETHYL,2- OR 5-CYANOPYRIMIDINES AS INTERMEDIATES OF ANTICOAGULANTS IN EXTRACORPOREAL CIRCULATION (HEART-LUNG MACHINE, HEMODIALYSIS) | BASF AKTIENGESELLSCHAFT (DE) | 2000-02-29 | — | — | US | disclosed |
| EP-0873356-A1 | NOVEL DIPEPTIDE AMIDINES AS THROMBIN INHIBITORS | BASF AKTIENGESELLSCHAFT (DE) | 1998-10-28 | — | — | EP | disclosed |
| WO-1996025426-A1 | NOVEL DIPEPTIDE AMIDINES AS THROMBIN INHIBITORS | BASF AKTIENGESELLSCHAFT (DE) | 1996-08-22 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060275913-A1 | Carbonyl compound scavenger and method of quantifying carbonyl compound using the same | CBR1, CBR3, HAO2 | TRPV4 531/4885HTR2A 3433/4885KCNH2 99/4885 |
| US-20020169318-A1 | Novel thrombin inhibitors | TFPI, SERPINC1, F11 | TRPV4 4468/4885HTR2A 3737/4885KCNH2 3150/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.