SCHEMBL3897264

SCHEMBL3897264

B(Oc1cccc(-c2ccc(-c3ccccc3)c3ccccc23)c1)Oc1cccc(-c2ccc(-c3ccccc3)c3ccccc23)c1

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GSTP1 P09211 1/20 0.39
BRD4 O60885 1/20 0.39
GPR84 Q9NQS5 1/20 0.36
DGAT2 Q96PD7 2/20 0.36
CYP1A2 P05177 1/20 0.36
CYP3A4 P08684 1/20 0.36
VDR P11473 1/20 0.36
CYP2C9 P11712 1/20 0.36
CYP2B6 P20813 1/20 0.36
AHR P35869 1/20 0.36
NR1I3 Q14994 1/20 0.36
DHODH Q02127 1/20 0.35
ADORA2A P29274 2/20 0.35
MGAT2 Q10469 1/20 0.35
BACE1 P56817 1/20 0.34
ALOX5 P09917 1/20 0.34
HPGD P15428 2/20 0.34
KDM4E B2RXH2 1/20 0.34
MEN1 O00255 1/20 0.34
ALDH1A1 P00352 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4530341 0.82 MAOA (0.43) CYP1A2CYP3A4CYP2C9CYP2B6BACE1
SCHEMBL3888994 0.81 ESR1 (0.40) GPR84CYP1A2CYP3A4VDRCYP2C9
SCHEMBL6926344 0.74 PTGS1 (0.41) GSTP1CYP1A2CYP3A4CYP2C9HPGD
SCHEMBL25818576 0.74 FABP4 (0.42) GSTP1BACE1HPGDKDM4EALDH1A1
SCHEMBL10197719 0.74 CRHBP (0.39) BRD4GPR84DGAT2DHODHMGAT2
SCHEMBL11971603 0.73 NQO1 (0.46) GPR84BACE1ALOX5HPGDKDM4E
SCHEMBL11978650 0.73 MCL1 (0.43) GPR84CYP2C9HPGDKDM4EMEN1
SCHEMBL3415539 0.72 ALDH1A1 (0.53) BRD4BACE1ALOX5HPGDKDM4E
SCHEMBL29728323 0.72 ALDH1A1 (0.53) BRD4BACE1ALOX5HPGDKDM4E
SCHEMBL3689307 0.72 HSD17B1 (0.53) GSTP1CYP1A2CYP3A4CYP2C9CYP2B6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1903020-B1 BIPHENYL DERIVATIVES, ORGANIC ELECTROLUMINESCENT MATERIALS, AND ORGANIC ELECTROLUMINESCENT DEVICES MADE BY USING THE SAME IDEMITSU KOSAN CO (JP) 2014-03-19 EP disclosed
US-7560604-B2 Biphenyl derivative, material for organic electroluminescence device, and organic electroluminescence device using the same IDEMITSU KOSAN CO., LTD. (JP) 2009-07-14 US disclosed
EP-1903020-A1 BIPHENYL DERIVATIVES, ORGANIC ELECTROLUMINESCENT MATERIALS, AND ORGANIC ELECTROLUMINESCENT DEVICES MADE BY USING THE SAME IDEMITSU KOSAN CO., LTD. (JP) 2008-03-26 EP disclosed
US-20070013296-A1 Biphenyl derivative, material for organic electroluminescence device, and organic electroluminescence device using the same IDEMITSU KOSAN CO., LTD. (JP) 2007-01-18 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070013296-A1 Biphenyl derivative, material for organic electroluminescence device, and organic electroluminescence device using the same EED, BMI1, EBPL GSTP1 1085/4885BRD4 167/4885GPR84 3986/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.