Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 1/20 | 0.41 |
| ▸ | FFAR4 | Q5NUL3 | 4/20 | 0.39 |
| ▸ | FEN1 | P39748 | 2/20 | 0.36 |
| ▸ | APP | P05067 | 2/20 | 0.35 |
| ▸ | FASN | P49327 | 1/20 | 0.35 |
| ▸ | MTOR | P42345 | 1/20 | 0.35 |
| ▸ | CHRNA7 | P36544 | 2/20 | 0.34 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.34 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.34 |
| ▸ | MAP3K11 | Q16584 | 1/20 | 0.34 |
| ▸ | THRA | P10827 | 1/20 | 0.34 |
| ▸ | THRB | P10828 | 1/20 | 0.34 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3897348 | 0.90 | PTGS2 (0.41) | PTGS2APPMTORKCNH2MCL1 | |
| SCHEMBL3891613 | 0.90 | APP (0.42) | PTGS2APPMTORMCL1MAP3K11 | |
| SCHEMBL3893664 | 0.87 | PTGS2 (0.39) | PTGS2APPMTORMCL1MAP3K11 | |
| SCHEMBL3675185 | 0.86 | THRA (0.49) | FFAR4MTORTHRATHRB | |
| SCHEMBL3884668 | 0.86 | PTGS2 (0.42) | PTGS2MTORCHRNA7MAP3K11ENPP2 | |
| SCHEMBL3677105 | 0.83 | THRA (0.38) | PTGS2FFAR4FEN1FASNMTOR | |
| SCHEMBL3882901 | 0.80 | PTGS2 (0.43) | PTGS2APPCHRNA7MCL1MAP3K11 | |
| SCHEMBL3882575 | 0.79 | PTGS2 (0.43) | PTGS2APPCHRNA7MCL1MAP3K11 | |
| SCHEMBL3883008 | 0.79 | PTGS2 (0.41) | PTGS2MTORCHRNA7MAP3K11ENPP2 | |
| SCHEMBL3884976 | 0.79 | PPARG (0.40) | FFAR4MTOR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1477472-B1 | SUBSTITUTED PHENYLALKANOIC ACID DERIVATIVE AND USE THEREOF | ASAHI KASEI PHARMA CORP (JP) | 2009-01-14 | — | — | EP | claimed |