SCHEMBL3898652

SCHEMBL3898652

CN(C)C(=S)Oc1ccc2ccc(OC(=S)N(C)C)cc2c1

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 4/20 0.53
MAPT P10636 3/20 0.53
TDP1 Q9NUW8 2/20 0.53
CYP1A2 P05177 2/20 0.53
NR1I2 O75469 2/20 0.53
CYP3A4 P08684 1/20 0.53
CYP2C9 P11712 1/20 0.53
MAPK1 P28482 1/20 0.53
CYP2C19 P33261 1/20 0.53
HTR2B P41595 1/20 0.53
CYP51A1 Q16850 1/20 0.53
NCEH1 Q6PIU2 1/20 0.46
ALDH1A1 P00352 2/20 0.40
KMT2A Q03164 4/20 0.39
MEN1 O00255 3/20 0.39
SMN1; SMN2 Q16637 2/20 0.39
HTT P42858 2/20 0.39
RAB9A P51151 3/20 0.38
CYP2A6 P11509 1/20 0.38
TSHR P16473 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30772982 1.00 LMNA (0.53) LMNAMAPTTDP1CYP1A2NR1I2
SCHEMBL20335346 0.90 NCEH1 (0.62) LMNAMAPTTDP1CYP1A2NR1I2
SCHEMBL4072743 0.85 NCEH1 (0.66) LMNAMAPTTDP1CYP1A2NR1I2
SCHEMBL10845423 0.83 HGFAC (0.51) LMNAMAPTTDP1CYP1A2NR1I2
SCHEMBL9711125 0.81 NCEH1 (0.45) LMNAMAPTTDP1CYP1A2NR1I2
SCHEMBL9351842 0.81 NCEH1 (0.45) LMNAMAPTTDP1CYP1A2NR1I2
SCHEMBL3553411 0.79 HGFAC (0.53) MAPTNCEH1ALDH1A1KMT2AHTT
SCHEMBL24372709 0.78 L3MBTL1 (0.37) LMNAMAPTTDP1CYP1A2NR1I2
SCHEMBL2672213 0.78 CYP1A2 (0.44) LMNAMAPTTDP1CYP1A2NR1I2
SCHEMBL7017109 0.78 CA2 (0.45) LMNAMAPTTDP1CYP1A2NR1I2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240217926-A1 1,6-NAPHTHALENEDITHIOL PRODUCT AND PROCESS FOR PRODUCING THE SAME SUGAI CHEMICAL INDUSTRY CO., LTD. (JP) 2024-07-04 US disclosed
EP-4296264-A1 1,6-NAPHTHALENEDITHIOL AND METHOD FOR PRODUCING SAME SUGAI CHEMICAL INDUSTRY CO., LTD. (JP) 2023-12-27 EP disclosed
CN-117157277-A 1, 6-naphthalene dithiol and process for producing the same 菅井化学工业株式会社 2023-12-01 CN disclosed
WO-2023176299-A1 1,6-NAPHTHALENEDITHIOL AND METHOD FOR PRODUCING SAME スガイ化学工業株式会社 2023-09-21 WO disclosed
EP-1831728-B1 DISPLAYS HAVING A HIGH REFRACTIVE INDEX, DURABLE HARDCOAT LAYER 3M INNOVATIVE PROPERTIES CO (US) 2009-07-29 EP disclosed
US-7491441-B2 High refractive index, durable hard coats 3M INNOVATIVE PROPERTIES COMPANY (US) 2009-02-17 US disclosed
EP-1831728-A2 HIGH REFRACTIVE INDEX, DURABLE HARD COATS 3M Innovative Properties Company (US) 2007-09-12 EP disclosed
WO-2006073773-A2 HIGH REFRACTIVE INDEX, DURABLE HARD COATS 3M INNOVATIVE PROPERTIES COMPANY (US) 2006-07-13 WO disclosed
US-20060147702-A1 High refractive index, durable hard coats 3M INNOVATIVE PROPERTIES COMPANY 2006-07-06 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240217926-A1 1,6-NAPHTHALENEDITHIOL PRODUCT AND PROCESS FOR PRODUCING THE SAME SULT1A1, SULT2A1, DNTT LMNA 2339/4885MAPT 2207/4885TDP1 1654/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.