Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 6/20 | 0.40 |
| ▸ | CA1 | P00915 | 5/20 | 0.40 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.37 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.37 |
| ▸ | AKT1 | P31749 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.35 |
| ▸ | PPARG | P37231 | 1/20 | 0.35 |
| ▸ | PPARA | Q07869 | 1/20 | 0.35 |
| ▸ | NAMPT | P43490 | 1/20 | 0.35 |
| ▸ | F2RL1 | P55085 | 1/20 | 0.35 |
| ▸ | CA12 | O43570 | 2/20 | 0.35 |
| ▸ | CA7 | P43166 | 1/20 | 0.35 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.35 |
| ▸ | CA9 | Q16790 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7101278 | 0.87 | CA2 (0.41) | CA2CA1CYP4F2CYP4A11GAA | |
| SCHEMBL3786555 | 0.86 | TDP1 (0.50) | CA1AKT1PPARGPPARACA12 | |
| SCHEMBL28286450 | 0.84 | CA2 (0.37) | CA2CA1PPARGPPARA | |
| SCHEMBL4409312 | 0.84 | CYP4F2 (0.44) | CYP4F2CYP4A11F2RL1 | |
| SCHEMBL27413860 | 0.80 | CA1 (0.42) | CA2CA1 | |
| SCHEMBL1409917 | 0.78 | F2RL1 (0.47) | CA2CA1CYP4F2CYP4A11F2RL1 | |
| SCHEMBL17844769 | 0.78 | ADRB2 (0.49) | CA1AKT1CA12CA7CA14 | |
| SCHEMBL23859885 | 0.78 | CA1 (0.37) | CA2CA1GAAPPARGCA12 | |
| SCHEMBL30678936 | 0.77 | ALOX5 (0.48) | CA1AKT1CA12CA7CA14 | |
| SCHEMBL11961188 | 0.77 | CA2 (0.55) | CA2CA1NAMPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0976722-B1 | BENZAMIDINE DERIVATIVES | AJINOMOTO KK (JP) | 2009-03-11 | — | — | EP | disclosed |
| US-7396844-B1 | Benzamidine derivatives | AJINOMOTO CO., INC. (JP) | 2008-07-08 | — | — | US | disclosed |
| EP-0976722-A1 | BENZAMIDINE DERIVATIVES | Ajinomoto Co., Inc. (JP) | 2000-02-02 | — | — | EP | disclosed |