Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRA1 | P14867 | 1/20 | 0.56 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.56 |
| ▸ | CA2 | P00918 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.36 |
| ▸ | CYP2A6 | P11509 | 2/20 | 0.36 |
| ▸ | TRPA1 | O75762 | 2/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | ACHE | P22303 | 1/20 | 0.35 |
| ▸ | CA1 | P00915 | 1/20 | 0.35 |
| ▸ | CA7 | P43166 | 1/20 | 0.35 |
| ▸ | CA9 | Q16790 | 1/20 | 0.35 |
| ▸ | KIF11 | P52732 | 1/20 | 0.34 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.34 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5061062 | 0.85 | CA2 (0.55) | GABRA1GABRB2CA2ALDH1A1TSHR | |
| SCHEMBL25374949 | 0.79 | GABRA1 (0.39) | GABRA1GABRB2CA2ALDH1A1TSHR | |
| SCHEMBL201778 | 0.76 | — | — | |
| SCHEMBL3167832 | 0.75 | GABRA1 (0.60) | GABRA1GABRB2CA2ALDH1A1TSHR | |
| SCHEMBL30660859 | 0.75 | GABRA1 (0.60) | GABRA1GABRB2CA2ALDH1A1TSHR | |
| SCHEMBL14877302 | 0.75 | GABRA1 (0.60) | GABRA1GABRB2CA2ALDH1A1TSHR | |
| SCHEMBL30407772 | 0.74 | GABRA1 (0.58) | GABRA1GABRB2CA2ALDH1A1TSHR | |
| SCHEMBL542212 | 0.74 | GABRA1 (0.58) | GABRA1GABRB2CA2ALDH1A1TSHR | |
| SCHEMBL5496813 | 0.74 | GABRA1 (0.58) | GABRA1GABRB2CA2ALDH1A1TSHR | |
| SCHEMBL27934749 | 0.73 | CYP1A2 (0.47) | GABRA1GABRB2CA2ALDH1A1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8609807-B2 | Method of producing low-dust granules from polymer additives | BASF SE (DE) | 2013-12-17 | — | — | US | disclosed |
| US-20090194617-A1 | Method of producing low-dust granules from polymer additives | CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) | 2009-08-06 | — | — | US | disclosed |
| EP-1567536-B1 | LIQUID PHENOLIC SULPHUR-CONTAINING ANTIOXIDANTS | CIBA HOLDING INC (CH) | 2009-03-25 | — | — | EP | disclosed |
| US-7507853-B2 | Process for the preparation of phenolic carboxylic acid derivatives by enzymatic catalysis | CIBA SPECIALTY CHEMICALS CORPORATION (US) | 2009-03-24 | — | — | US | disclosed |
| EP-1706451-B1 | METHOD OF PRODUCING LOW-DUST GRANULES FROM POLYMER ADDITIVES | CIBA SC HOLDING AG (CH) | 2007-05-09 | — | — | EP | disclosed |
| EP-1706451-A1 | METHOD OF PRODUCING LOW-DUST GRANULES FROM POLYMER ADDITIVES | Ciba Specialty Chemicals Holding Inc. (CH) | 2006-10-04 | — | — | EP | disclosed |
| US-20060116301-A1 | Liquid phenolic sulphur-containing antioxidants | CIBA SPECIALTY CHEMICALS CORP. | 2006-06-01 | — | — | US | disclosed |
| US-20060110807-A1 | Process for the preparation of phenolic carboxylic acid derivaties by enzymatic catalysis | CIBA SPECIALTY CHEMICALS CORP. | 2006-05-25 | — | — | US | disclosed |
| US-7026438-B2 | Liquid phenolic sulphur-containing antioxidants | CIBA SPECIALTY CHEMICALS CORP. (US) | 2006-04-11 | — | — | US | disclosed |
| EP-1567536-A1 | LIQUID PHENOLIC SULPHUR-CONTAINING ANTIOXIDANTS | Ciba SC Holding AG (CH) | 2005-08-31 | — | — | EP | disclosed |
| WO-2005071008-A1 | METHOD OF PRODUCING LOW-DUST GRANULES FROM POLYMER ADDITIVES | CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) | 2005-08-04 | — | — | WO | disclosed |
| EP-1549752-A1 | PROCESS FOR THE PREPARATION OF PHENOLIC CARBOXYLIC ACID DERIVATIVES BY ENZYMATIC CATALYSIS | Ciba SC Holding AG (CH) | 2005-07-06 | — | — | EP | disclosed |
| US-20040267042-A1 | Liquid phenolic sulphur-containing antioxidants | CIBA SPECIALTY CHEMICALS CORP. | 2004-12-30 | — | — | US | disclosed |
| WO-2004050671-A1 | LIQUID PHENOLIC SULPHUR-CONTAINING ANTIOXIDANTS | CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) | 2004-06-17 | — | — | WO | disclosed |
| WO-2004033699-A1 | PROCESS FOR THE PREPARATION OF PHENOLIC CARBOXYLIC ACID DERIVATIVES BY ENZYMATIC CATALYSIS | CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) | 2004-04-22 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040267042-A1 | Liquid phenolic sulphur-containing antioxidants | TST, COMT, GPX4 | GABRA1 2852/4885GABRB2 2385/4885CA2 4239/4885 |
| US-20060116301-A1 | Liquid phenolic sulphur-containing antioxidants | TST, COMT, SOD1 | GABRA1 2520/4885GABRB2 1999/4885CA2 4174/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.