Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP2 | P08253 | 4/20 | 0.50 |
| ▸ | MMP9 | P14780 | 4/20 | 0.50 |
| ▸ | MMP3 | P08254 | 2/20 | 0.50 |
| ▸ | MMP8 | P22894 | 1/20 | 0.41 |
| ▸ | MMP13 | P45452 | 1/20 | 0.41 |
| ▸ | BID | P55957 | 3/20 | 0.39 |
| ▸ | MCL1 | Q07820 | 3/20 | 0.39 |
| ▸ | BCL2L1 | Q07817 | 2/20 | 0.39 |
| ▸ | BAK1 | Q16611 | 2/20 | 0.39 |
| ▸ | KAT8 | Q9H7Z6 | 2/20 | 0.39 |
| ▸ | PPARA | Q07869 | 2/20 | 0.39 |
| ▸ | PPARG | P37231 | 1/20 | 0.39 |
| ▸ | EP300 | Q09472 | 1/20 | 0.39 |
| ▸ | KAT2A | Q92830 | 1/20 | 0.39 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.39 |
| ▸ | KAT5 | Q92993 | 1/20 | 0.39 |
| ▸ | SAE1 | Q9UBE0 | 1/20 | 0.39 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.38 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.38 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3897034 | 0.81 | MMP2 (0.56) | MMP2MMP9MMP3MMP8MMP13 | |
| SCHEMBL3896300 | 0.81 | MMP2 (0.56) | MMP2MMP9MMP3MMP8MMP13 | |
| SCHEMBL29010133 | 0.80 | MMP2 (0.65) | MMP2MMP9MMP3MMP8MMP13 | |
| SCHEMBL4449571 | 0.75 | MMP2 (0.48) | MMP2MMP9MMP3MMP8MMP13 | |
| SCHEMBL27807652 | 0.73 | SCN9A (0.37) | MMP2MMP9MMP3MMP8MMP13 | |
| SCHEMBL27457527 | 0.72 | CTRC (0.37) | BIDMCL1BCL2L1BAK1KAT8 | |
| Benzene SCHEMBL8729420 | 0.66 | LIPG (0.67) | BIDMCL1BCL2L1BAK1KAT8 | |
| SCHEMBL7054345 | 0.66 | LIPG (0.49) | BIDMCL1BCL2L1BAK1KAT8 | |
| SCHEMBL29432879 | 0.66 | LIPG (0.49) | BIDMCL1BCL2L1BAK1KAT8 | |
| SCHEMBL18153979 | 0.66 | LIPG (0.49) | BIDMCL1BCL2L1BAK1KAT8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6224791-B1 | PHENYLBENZOFURAN-2-ONE WITH PHOSPHITE | DOVER CHEMICAL CORPORATION | 2001-05-01 | — | — | US | claimed |
| WO-1999003915-A1 | LACTONE/PHOSPHITE BLENDS | DOVER CHEMICAL CORPORATION (US) | 1999-01-28 | — | — | WO | claimed |
| EP-1692150-A4 | PROCESS FOR MANUFACTURE OF PENTAERYTHRITOL DIPHOSPHITES | DOVER CHEMICAL CORP (US) | 2009-02-25 | — | — | EP | disclosed |
| US-7470735-B2 | Phenol-free phosphites | DOVER CHEMICAL CORPORATION (US) | 2008-12-30 | — | — | US | disclosed |
| US-7342060-B2 | Process for manufacture of pentaerythritol diphosphites | DOVER CHEMICAL CORPORATION (US) | 2008-03-11 | — | — | US | disclosed |
| EP-1692150-A2 | PROCESS FOR MANUFACTURE OF PENTAERYTHRITOL DIPHOSPHITES | Dover Chemical Corporation (US) | 2006-08-23 | — | — | EP | disclosed |
| WO-2005113665-A2 | PHENOL-FREE PHOSPHITES | DOVER CHEMICAL CORPORATION (US) | 2005-12-01 | — | — | WO | disclosed |
| WO-2005060500-A2 | PROCESS FOR MANUFACTURE OF PENTAERYTHRITOL DIPHOSPHITES | DOVER CHEMICAL CORPORATION (US) | 2005-07-07 | — | — | WO | disclosed |
| US-20050131244-A1 | PROCESS FOR MANUFACTURE OF PENTAERYTHRITOL DIPHOSPHITES | DOVER CHEMICAL CORPORATION (US) | 2005-06-16 | — | — | US | disclosed |
| US-20040180999-A1 | PHENOL-FREE PHOSPHITES | DOVER CHEMICAL CORPORATION (US) | 2004-09-16 | — | — | US | disclosed |
| US-6770693-B2 | COMPRISING BIS-(2,4-DICUMYLPHENYL) PENTAERYTHRITOL DIPHOSPHITE AND HINDERED PHENOL ANTIOXIDANTS USEFUL AS STABILIZERS AGAINST THERMOOXIDATIVE DEGRADATION OF POLYMERS DURING MELT PROCESSING | DOVE CHEMICAL CORPORATION | 2004-08-03 | — | — | US | disclosed |
| US-20020040081-A1 | Blends of phosphites and antioxidants | DOVER CHEMICAL | 2002-04-04 | — | — | US | disclosed |
| US-6224791-B1 | PHENYLBENZOFURAN-2-ONE WITH PHOSPHITE | DOVER CHEMICAL CORPORATION | 2001-05-01 | — | — | US | disclosed |
| WO-1999003915-A1 | LACTONE/PHOSPHITE BLENDS | DOVER CHEMICAL CORPORATION (US) | 1999-01-28 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050131244-A1 | PROCESS FOR MANUFACTURE OF PENTAERYTHRITOL DIPHOSPHITES | GNPAT, DCTPP1, DERA | MMP2 3937/4885MMP9 4578/4885MMP3 4744/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.