Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 1/20 | 0.51 |
| ▸ | HTR7 | P34969 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.49 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.49 |
| ▸ | BCL6 | P41182 | 1/20 | 0.48 |
| ▸ | ELOVL1 | Q9BW60 | 1/20 | 0.47 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.47 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | KCNH3 | Q9ULD8 | 1/20 | 0.44 |
| ▸ | SPR | P35270 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | LTA4H | P09960 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15904401 | 0.86 | L3MBTL1 (0.63) | RAB9AHTR7MEN1KMT2ABCL6 | |
| SCHEMBL10559761 | 0.85 | RAB9A (0.71) | RAB9AMEN1KMT2ACYP11B1CYP11B2 | |
| SCHEMBL10875855 | 0.83 | POLB (0.54) | RAB9AMEN1KMT2AL3MBTL1GAA | |
| SCHEMBL3911086 | 0.83 | GBA1 (0.56) | RAB9AMEN1KMT2ATAAR1L3MBTL1 | |
| SCHEMBL28679564 | 0.80 | TRPV1 (0.54) | RAB9AMEN1KMT2ABCL6GAA | |
| SCHEMBL6631070 | 0.79 | RAB9A (0.48) | RAB9AMEN1KMT2ABCL6POLB | |
| SCHEMBL3906998 | 0.78 | SPR (0.49) | RAB9AMEN1KMT2ACYP11B1CYP11B2 | |
| SCHEMBL2311052 | 0.78 | L3MBTL1 (0.73) | RAB9AHTR7TAAR1L3MBTL1KCNH3 | |
| SCHEMBL6176772 | 0.77 | CHRNA7 (0.57) | ELOVL1L3MBTL1GAAPOLB | |
| SCHEMBL5307781 | 0.76 | LTA4H (0.69) | RAB9AMEN1KMT2ABCL6L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2018364-A1 | THERAPEUTIC FLUOROETHYL UREAS | Allergan, Inc. (US) | 2009-01-28 | — | — | EP | disclosed |
| WO-2007137029-A1 | THERAPEUTIC FLUOROETHYL UREAS | ALLERGAN, INC. (US) | 2007-11-29 | — | — | WO | disclosed |