Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GBA1 | P04062 | 1/20 | 0.56 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.49 |
| ▸ | SGMS2 | Q8NHU3 | 1/20 | 0.48 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.47 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.47 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.47 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19198639 | 0.86 | PDE4B (0.62) | TAAR1KDM4EKMT2AGAALMNA | |
| SCHEMBL22196991 | 0.84 | RAB9A (0.54) | TAAR1KDM4EKMT2ALMNASGMS2 | |
| SCHEMBL3907142 | 0.83 | RAB9A (0.51) | TAAR1KDM4EKMT2AGAAL3MBTL1 | |
| SCHEMBL15904401 | 0.82 | L3MBTL1 (0.63) | GBA1KDM4EKMT2ACSNK2A1L3MBTL1 | |
| SCHEMBL3906108 | 0.80 | L3MBTL1 (0.66) | TAAR1KDM4EKMT2ALMNAGPR84 | |
| SCHEMBL9829440 | 0.80 | TAAR1 (0.53) | GBA1TAAR1KMT2AGAALMNA | |
| SCHEMBL3906998 | 0.78 | SPR (0.49) | TAAR1KDM4EKMT2ALMNAPDE4B | |
| SCHEMBL10875855 | 0.76 | POLB (0.54) | GBA1KDM4EKMT2AGAAL3MBTL1 | |
| SCHEMBL5307781 | 0.76 | LTA4H (0.69) | GBA1KDM4EKMT2AL3MBTL1MEN1 | |
| SCHEMBL3901187 | 0.75 | MAPT (0.57) | KDM4EKMT2AL3MBTL1MEN1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2018364-A1 | THERAPEUTIC FLUOROETHYL UREAS | Allergan, Inc. (US) | 2009-01-28 | — | — | EP | disclosed |
| WO-2007137029-A1 | THERAPEUTIC FLUOROETHYL UREAS | ALLERGAN, INC. (US) | 2007-11-29 | — | — | WO | disclosed |