Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR2 | O95136 | 1/20 | 0.39 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.39 |
| ▸ | CNR1 | P21554 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | OPRM1 | P35372 | 4/20 | 0.36 |
| ▸ | OPRL1 | P41146 | 3/20 | 0.36 |
| ▸ | OPRD1 | P41143 | 2/20 | 0.36 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.36 |
| ▸ | MTNR1A | P48039 | 5/20 | 0.36 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.35 |
| ▸ | CTSA | P10619 | 1/20 | 0.35 |
| ▸ | NOTUM | Q6P988 | 2/20 | 0.35 |
| ▸ | MTNR1B | P49286 | 2/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3910650 | 0.87 | OPRM1 (0.43) | CNR1MAPTSMN1; SMN2OPRM1OPRD1 | |
| SCHEMBL3915781 | 0.84 | CNR1 (0.39) | CNR1MAPTOPRM1OPRD1OPRK1 | |
| SCHEMBL3903152 | 0.84 | OPRM1 (0.40) | CNR1MAPTSMN1; SMN2OPRM1OPRL1 | |
| SCHEMBL3902047 | 0.83 | MTNR1A (0.39) | CNR1MAPTMTNR1AMTNR1B | |
| SCHEMBL3907788 | 0.80 | TAAR1 (0.49) | S1PR2S1PR4MAPTSMN1; SMN2 | |
| SCHEMBL3902333 | 0.77 | HIF1A (0.42) | CNR1MAPTSMN1; SMN2HIF1A | |
| SCHEMBL3906134 | 0.75 | ROCK2 (0.40) | MAPTSMN1; SMN2MTNR1AMTNR1B | |
| SCHEMBL3907851 | 0.74 | HIF1A (0.42) | S1PR4MAPTOPRM1OPRD1OPRK1 | |
| SCHEMBL3905440 | 0.74 | HIF1A (0.40) | S1PR4MAPTSMN1; SMN2OPRM1MTNR1A | |
| SCHEMBL3904588 | 0.74 | P2RX7 (0.42) | CNR1MAPTSMN1; SMN2MTNR1AMTNR1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2018364-A1 | THERAPEUTIC FLUOROETHYL UREAS | Allergan, Inc. (US) | 2009-01-28 | — | — | EP | claimed |
| WO-2007137029-A1 | THERAPEUTIC FLUOROETHYL UREAS | ALLERGAN, INC. (US) | 2007-11-29 | — | — | WO | claimed |
| EP-2018364-A1 | THERAPEUTIC FLUOROETHYL UREAS | Allergan, Inc. (US) | 2009-01-28 | — | — | EP | disclosed |
| WO-2007137029-A1 | THERAPEUTIC FLUOROETHYL UREAS | ALLERGAN, INC. (US) | 2007-11-29 | — | — | WO | disclosed |