Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FABP4 | P15090 | 12/20 | 0.35 |
| ▸ | ACLY | P53396 | 4/20 | 0.34 |
| ▸ | ACHE | P22303 | 2/20 | 0.31 |
| ▸ | FABP5 | Q01469 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | GFER | P55789 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | ATM | Q13315 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3907369 | 1.00 | FABP4 (0.35) | FABP4ACLYACHEFABP5KDM4E | |
| SCHEMBL3896152 | 0.78 | PLA2G2A (0.34) | FABP4ACLYACHEKDM4EALDH1A1 | |
| SCHEMBL3899652 | 0.74 | ACLY (0.36) | FABP4ACLYACHEFABP5ALDH1A1 | |
| SCHEMBL3907870 | 0.72 | PLK1 (0.34) | FABP4ACLYACHEKDM4EALDH1A1 | |
| SCHEMBL3896155 | 0.71 | ACHE (0.35) | FABP4ACLYACHEKDM4EMEN1 | |
| SCHEMBL8997331 | 0.70 | ACHE (0.44) | ACHEKDM4EMEN1ALDH1A1KMT2A | |
| SCHEMBL8997349 | 0.70 | ACHE (0.44) | ACHEKDM4EMEN1ALDH1A1KMT2A | |
| SCHEMBL10516081 | 0.66 | FABP4 (0.35) | FABP4KDM4EMEN1ALDH1A1POLB | |
| SCHEMBL3902038 | 0.66 | ESR1 (0.36) | ACHEMEN1ALDH1A1POLBGAA | |
| SCHEMBL3898772 | 0.66 | ACHE (0.32) | ACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0916658-B1 | Assays utilizing improved chemiluminescent esters, thioesters and amides | NICHOLS INST DIAGNOSTICS (US) | 2009-03-18 | — | — | EP | disclosed |
| EP-0322926-B2 | Assays utilizing improved chemiluminescent esters, thioesters and amides | NICHOLS INST DIAGNOSTICS (US) | 2004-03-31 | — | — | EP | disclosed |
| EP-0322926-B1 | Assays utilizing improved chemiluminescent esters, thioesters and amides | NICHOLS INST DIAGNOSTICS (US) | 1999-08-11 | — | — | EP | disclosed |
| EP-0916658-A1 | Assays utilizing improved chemiluminescent esters, thioesters and amides | Nichols Institute Diagnostics (US) | 1999-05-19 | — | — | EP | disclosed |
| US-5284952-A | Sulfonyl substituted chemiluminescent labels and their conjugates, and assays therefrom | LONDON DIAGNOSTICS, INC. (US) | 1994-02-08 | — | — | US | disclosed |
| US-5284951-A | Aryl ester, thioester or amide of carboxylic acid substituted heterocyclic ring; quaternary compounds | LONDON DIAGNOSTICS, INC. (US) | 1994-02-08 | — | — | US | disclosed |
| WO-1989006231-A1 | ASSAYS UTILIZING IMPROVED CHEMILUMINESCENT ESTERS, THIOESTERS AND AMIDES | LONDON DIAGNOSTICS, INC. (US) | 1989-07-13 | — | — | WO | disclosed |
| EP-0322926-A2 | Assays utilizing improved chemiluminescent esters, thioesters and amides | LONDON DIAGNOSTICS, INC. (US) | 1989-07-05 | — | — | EP | disclosed |