Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLA2G2A | P14555 | 2/20 | 0.34 |
| ▸ | FABP4 | P15090 | 10/20 | 0.32 |
| ▸ | ACHE | P22303 | 1/20 | 0.32 |
| ▸ | ACLY | P53396 | 1/20 | 0.32 |
| ▸ | PLK1 | P53350 | 1/20 | 0.32 |
| ▸ | TRPV4 | Q9HBA0 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
| ▸ | PKM | P14618 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3907870 | 0.95 | PLK1 (0.34) | PLA2G2AFABP4ACHEACLYPLK1 | |
| SCHEMBL3902038 | 0.85 | ESR1 (0.36) | ACHEALDH1A1NPSR1 | |
| SCHEMBL3899652 | 0.84 | ACLY (0.36) | PLA2G2AFABP4ACHEACLYALDH1A1 | |
| SCHEMBL3898772 | 0.82 | ACHE (0.32) | ACHE | |
| SCHEMBL3911544 | 0.80 | POLB (0.41) | FABP4KDM4EALDH1A1 | |
| SCHEMBL3907369 | 0.78 | FABP4 (0.35) | FABP4ACHEACLYKDM4EALDH1A1 | |
| SCHEMBL3907367 | 0.78 | FABP4 (0.35) | FABP4ACHEACLYKDM4EALDH1A1 | |
| SCHEMBL3907421 | 0.76 | L3MBTL1 (0.36) | ACHEKDM4EALDH1A1HPGD | |
| SCHEMBL3904667 | 0.76 | ACHE (0.32) | ACHEALDH1A1NPSR1PKM | |
| SCHEMBL10480404 | 0.75 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0330433-B1 | Protected chemiluminescent labels | GEN PROBE INC (US) | 1996-04-17 | — | — | EP | claimed |
| EP-0916658-B1 | Assays utilizing improved chemiluminescent esters, thioesters and amides | NICHOLS INST DIAGNOSTICS (US) | 2009-03-18 | — | — | EP | disclosed |
| EP-0322926-B2 | Assays utilizing improved chemiluminescent esters, thioesters and amides | NICHOLS INST DIAGNOSTICS (US) | 2004-03-31 | — | — | EP | disclosed |
| EP-0322926-B1 | Assays utilizing improved chemiluminescent esters, thioesters and amides | NICHOLS INST DIAGNOSTICS (US) | 1999-08-11 | — | — | EP | disclosed |
| EP-0916658-A1 | Assays utilizing improved chemiluminescent esters, thioesters and amides | Nichols Institute Diagnostics (US) | 1999-05-19 | — | — | EP | disclosed |
| EP-0330433-B1 | Protected chemiluminescent labels | GEN PROBE INC (US) | 1996-04-17 | — | — | EP | disclosed |
| US-5338847-A | Hydrolytically stable chemiluminescent labels and their conjugates, and assays therefrom by adduct formation | LONDON DIAGNOSTICS, INC. (US) | 1994-08-16 | — | — | US | disclosed |
| US-5321136-A | Peri substituted fused ring chemiluminescent labels and their conjugates, and assays therefrom | LONDON DIAGNOSTICS, INC. (US) | 1994-06-14 | — | — | US | disclosed |
| US-5284952-A | Sulfonyl substituted chemiluminescent labels and their conjugates, and assays therefrom | LONDON DIAGNOSTICS, INC. (US) | 1994-02-08 | — | — | US | disclosed |
| US-5284951-A | Aryl ester, thioester or amide of carboxylic acid substituted heterocyclic ring; quaternary compounds | LONDON DIAGNOSTICS, INC. (US) | 1994-02-08 | — | — | US | disclosed |
| US-5283334-A | Side-chain functional chemiluminescent labels and their conjugates, and assays therefrom | LONDON DIAGNOSTICS, INC. (US) | 1994-02-01 | — | — | US | disclosed |
| WO-1989006231-A1 | ASSAYS UTILIZING IMPROVED CHEMILUMINESCENT ESTERS, THIOESTERS AND AMIDES | LONDON DIAGNOSTICS, INC. (US) | 1989-07-13 | — | — | WO | disclosed |
| EP-0322926-A2 | Assays utilizing improved chemiluminescent esters, thioesters and amides | LONDON DIAGNOSTICS, INC. (US) | 1989-07-05 | — | — | EP | disclosed |