Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | USP2 | O75604 | 1/20 | 0.34 |
| ▸ | GLA | P06280 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
| ▸ | PAX8 | Q06710 | 4/20 | 0.34 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.34 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.34 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.34 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3903700 | 1.00 | GAA (0.35) | GAALMNAMAPTUSP2GLA | |
| SCHEMBL3910570 | 0.86 | PAX8 (0.41) | GAALMNAPAX8ADRB2ADRB1 | |
| SCHEMBL3913543 | 0.86 | PAX8 (0.41) | GAALMNAPAX8ADRB2ADRB1 | |
| SCHEMBL3908167 | 0.76 | REN (0.37) | MAPTKMT2ATSHR | |
| SCHEMBL3908950 | 0.76 | RORC (0.32) | KMT2A | |
| SCHEMBL2683687 | 0.73 | CTSG (0.37) | LMNAGLAALDH1A1PTGDR2MEN1 | |
| SCHEMBL5278230 | 0.73 | CTSG (0.37) | LMNAGLAALDH1A1PTGDR2MEN1 | |
| SCHEMBL2683217 | 0.73 | CTSG (0.37) | LMNAGLAALDH1A1PTGDR2MEN1 | |
| SCHEMBL5382859 | 0.69 | DRD2 (0.39) | GAALMNAMAPTALDH1A1PAX8 | |
| SCHEMBL2683351 | 0.69 | DRD2 (0.39) | GAALMNAMAPTALDH1A1PAX8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2018862-A1 | Substituted piperidines as therapeutic compounds | Speedel Experimenta AG (CH) | 2009-01-28 | — | — | EP | disclosed |