Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.40 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.39 |
| ▸ | THRB | P10828 | 2/20 | 0.39 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 3/20 | 0.38 |
| ▸ | CA2 | P00918 | 3/20 | 0.38 |
| ▸ | CA12 | O43570 | 2/20 | 0.38 |
| ▸ | MMP2 | P08253 | 2/20 | 0.38 |
| ▸ | CA9 | Q16790 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26828326 | 0.98 | THRB (0.40) | SMN1; SMN2TP53TSHRMEN1KMT2A | |
| SCHEMBL4955886 | 0.90 | CA1 (0.47) | TP53TSHREPHX1CA1CA2 | |
| SCHEMBL30801441 | 0.87 | ZDHHC7 (0.50) | TP53TSHRKMT2AALDH1A1EPHX1 | |
| SCHEMBL3917565 | 0.86 | TSHR (0.48) | SMN1; SMN2TSHRMEN1KMT2AALDH1A1 | |
| SCHEMBL13545056 | 0.85 | TP53 (0.44) | SMN1; SMN2TP53TSHRMEN1KMT2A | |
| SCHEMBL38665252 | 0.85 | ZDHHC7 (0.51) | TSHREPHX1CA1CA2 | |
| SCHEMBL10256655 | 0.84 | TP53 (0.41) | SMN1; SMN2TP53TSHRMEN1KMT2A | |
| SCHEMBL5009517 | 0.83 | NAAA (0.45) | SMN1; SMN2TSHRALDH1A1NPSR1THRB | |
| SCHEMBL9588848 | 0.81 | TP53 (0.44) | SMN1; SMN2TP53TSHRMEN1KMT2A | |
| SCHEMBL12208613 | 0.81 | TP53 (0.44) | SMN1; SMN2TP53TSHRMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108689875-A | A kind of fenhexamid and its synthetic method | 陕西恒润化学工业有限公司 | 2018-10-23 | — | — | CN | claimed |
| CN-1200703-C | Use of pentanoate derivant | ONO PHARMACEUTICAL CO (JP) | 2005-05-11 | — | — | CN | claimed |
| CN-1322524-A | Use of pentanoate derivant | ONO PHARMACEUTICAL CO (JP) | 2001-11-21 | — | — | CN | claimed |
| CN-108689875-A | A kind of fenhexamid and its synthetic method | 陕西恒润化学工业有限公司 | 2018-10-23 | — | — | CN | disclosed |
| CN-108689875-A | A kind of fenhexamid and its synthetic method | 陕西恒润化学工业有限公司 | 2018-10-23 | — | — | CN | disclosed |
| US-7569608-B2 | Pentanoic acid derivatives | ONO PHARMACEUTICAL CO., LTD. (JP) | 2009-08-04 | — | — | US | disclosed |
| US-7569609-B2 | Pentanoic acid derivatives | ONO PHARMACEUTICAL CO., LTD. (JP) | 2009-08-04 | — | — | US | disclosed |
| US-7176240-B2 | Pentanoic acid derivatives | ONO PHARMACEUTICAL CO., LTD. (JP) | 2007-02-13 | — | — | US | disclosed |
| US-20050267167-A1 | Pentanoic acid derivatives | ONO PHARMACEUTICAL CO., LTD. | 2005-12-01 | — | — | US | disclosed |
| US-20050267168-A1 | Pentanoic acid derivatives | ONO PHARMACEUTICAL CO., LTD. | 2005-12-01 | — | — | US | disclosed |
| US-20050261371-A1 | Pentanoic acid derivatives | ONO PHARMACEUTICAL CO., LTD. | 2005-11-24 | — | — | US | disclosed |
| CN-1200703-C | Use of pentanoate derivant | ONO PHARMACEUTICAL CO (JP) | 2005-05-11 | — | — | CN | disclosed |
| US-20030096802-A1 | Pentanoic acid derivatives | ONO PHARMACEUTICAL CO., LTD. | 2003-05-22 | — | — | US | disclosed |
| CN-1083419-C | Pentanoic acid derivatives, process for their preparation, pharmaceutical compositions containing them and their use | ONO PHARMACEUTICAL CO (JP) | 2002-04-24 | — | — | CN | disclosed |
| CN-1322524-A | Use of pentanoate derivant | ONO PHARMACEUTICAL CO (JP) | 2001-11-21 | — | — | CN | disclosed |
| US-6201021-B1 | TREATMENT OF DISEASES INDUCED BY REACTIVE ASTROCYTES | ONO PHARMACEUTICAL CO., LTD. (JP) | 2001-03-13 | — | — | US | disclosed |
| EP-0632008-B1 | Pentanoic acid derivatives | ONO PHARMACEUTICAL CO (JP) | 1998-02-04 | — | — | EP | disclosed |
| CN-1100408-A | Pentanoic acid derivatives | ONO PHARMACEUTICAL CO (JP) | 1995-03-22 | — | — | CN | disclosed |
| EP-0632008-A1 | Pentanoic acid derivatives | ONO PHARMACEUTICAL CO., LTD. (JP) | 1995-01-04 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050267168-A1 | Pentanoic acid derivatives | FFAR3, FFAR1, HCAR3 | SMN1; SMN2 373/4885TP53 2336/4885TSHR 50/4885 |
| US-20030096802-A1 | Pentanoic acid derivatives | FFAR3, FPR1, FPR3 | SMN1; SMN2 138/4885TP53 3314/4885TSHR 408/4885 |
| US-20050267167-A1 | Pentanoic acid derivatives | FFAR3, FFAR1, HCAR3 | SMN1; SMN2 373/4885TP53 2336/4885TSHR 50/4885 |
| US-20050261371-A1 | Pentanoic acid derivatives | FFAR3, FFAR1, HCAR3 | SMN1; SMN2 402/4885TP53 2484/4885TSHR 65/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.