Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 2/20 | 0.52 |
| ▸ | CA2 | P00918 | 2/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.50 |
| ▸ | HPGD | P15428 | 4/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | HTT | P42858 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | XBP1 | P17861 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.48 |
| ▸ | CA12 | O43570 | 1/20 | 0.48 |
| ▸ | CA7 | P43166 | 1/20 | 0.48 |
| ▸ | CA9 | Q16790 | 1/20 | 0.48 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.47 |
| ▸ | XDH | P47989 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL67540 | 0.86 | ALDH1A1 (0.62) | CA1CA2ALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL475746 | 0.86 | CA1 (0.61) | CA1CA2ALDH1A1HPGDSMN1; SMN2 | |
| Methyl 3,5-Dimethoxybenzoate SCHEMBL204865 | 0.86 | CA1 (0.61) | CA1CA2ALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL588343 | 0.86 | ALDH1A1 (0.62) | CA1CA2ALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL1188720 | 0.82 | TPMT (0.61) | CA1CA2HPGDKDM4ECA12 | |
| SCHEMBL30251625 | 0.82 | TPMT (0.61) | CA1CA2HPGDKDM4ECA12 | |
| SCHEMBL986399 | 0.82 | HPGD (0.44) | HPGDMAPTKDM4EGAAPOLB | |
| SCHEMBL1188363 | 0.82 | LMNA (0.47) | ALDH1A1HPGDSMN1; SMN2MEN1KMT2A | |
| SCHEMBL30597928 | 0.82 | ALDH1A1 (0.45) | CA1CA2ALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL28543503 | 0.82 | ALDH1A1 (0.45) | CA1CA2ALDH1A1HPGDSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2024353-A2 | PYRAZOLE COMPOUNDS | Pfizer Products Inc. (US) | 2009-02-18 | — | — | EP | disclosed |
| WO-2007105058-A2 | PYRAZOLE COMPOUNDS | PFIZER PRODUCTS INC. (US) | 2007-09-20 | — | — | WO | disclosed |