Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 5/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.53 |
| ▸ | TSHR | P16473 | 2/20 | 0.53 |
| ▸ | ACHE | P22303 | 1/20 | 0.49 |
| ▸ | GFER | P55789 | 2/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 3/20 | 0.44 |
| ▸ | HSD17B2 | P37059 | 2/20 | 0.44 |
| ▸ | CYTH2 | Q99418 | 3/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10913560 | 0.85 | GAA (0.56) | GAAALDH1A1TSHRGFERSMN1; SMN2 | |
| SCHEMBL743630 | 0.83 | LMNA (0.65) | GAAALDH1A1TSHRGFERSMN1; SMN2 | |
| SCHEMBL3950097 | 0.81 | GAA (0.53) | GAAALDH1A1TSHRGFERSMN1; SMN2 | |
| SCHEMBL1868303 | 0.81 | ALDH1A1 (0.56) | GAAALDH1A1TSHRSMN1; SMN2LMNA | |
| SCHEMBL7129901 | 0.80 | GAA (0.51) | GAAALDH1A1TSHRGFERSMN1; SMN2 | |
| SCHEMBL8018706 | 0.80 | GAA (0.51) | GAAALDH1A1TSHRGFERSMN1; SMN2 | |
| SCHEMBL1094124 | 0.80 | ALDH1A1 (0.48) | GAAALDH1A1TSHRGFERSMN1; SMN2 | |
| SCHEMBL1225075 | 0.79 | LMNA (0.65) | GAAALDH1A1TSHRACHEGFER | |
| SCHEMBL9202081 | 0.79 | ALDH1A1 (0.50) | GAAALDH1A1TSHRGFERSMN1; SMN2 | |
| SCHEMBL1685394 | 0.79 | BRD4 (0.51) | GAAALDH1A1TSHRGFERSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1472259-B1 | TETRAPYRROLIC MACROCYCLES AS PHOTODYNAMIC AGENTS | CIPAN COMP IND PROD (PT) | 2009-09-02 | — | — | EP | claimed |
| EP-0607193-B1 | TRIAZOLE ANTIFUNGAL AGENTS | PFIZER LTD (GB) | 2000-09-13 | — | — | EP | claimed |
| EP-0460940-B1 | Pesticidal 1-arylpyrroles | RHONE POULENC AGROCHIMIE (FR) | 1999-01-27 | — | — | EP | claimed |
| EP-0396427-B1 | Pesticidal 1-arylimidazoles | RHONE POULENC AGROCHIMIE (FR) | 1995-09-13 | — | — | EP | claimed |
| EP-0071662-B1 | METHOD FOR MANUFACTURING LOW DENSITY RUBBER FOAMED BODY | Toyo Rubber Chemical Industrial Corporation (JP) | 1986-11-12 | — | — | EP | claimed |
| EP-0004172-B1 | BENZOCYCLOHEPTAPYRANS, THEIR PREPARATION AND PHARMACEUTICAL FORMULATIONS CONTAINING THEM | ELI LILLY AND COMPANY (US) | 1982-04-07 | — | — | EP | claimed |
| EP-2027096-B1 | SUBSTITUTED ARYLIMIDAZ0L0NE AND TRIAZ0L0NE AS INHIBITORS OF VASOPRESSIN RECEPTORS | Bayer Pharma AG (DE) | 2012-05-23 | — | — | EP | disclosed |
| EP-2027096-A1 | SUBSTITUTED ARYLIMIDAZ0L0NE AND TRIAZ0L0NE AS INHIBITORS OF VASOPRESSIN RECEPTORS | Bayer HealthCare AG (DE) | 2009-02-25 | — | — | EP | disclosed |
| WO-2007134862-A1 | SUBSTITUTED ARYLIMIDAZ0L0NE AND TRIAZ0L0NE AS INHIBITORS OF VASOPRESSIN RECEPTORS | BAYER HEALTHCARE AG (DE) | 2007-11-29 | — | — | WO | disclosed |