SCHEMBL8018706

SCHEMBL8018706

Cc1ccc(O)cc1S(=O)(=O)NS(C)(=O)=O

nearest known ligand 0.51

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
GAA P10253 5/20 0.51
ALDH1A1 P00352 3/20 0.51
TSHR P16473 2/20 0.51
GFER P55789 2/20 0.46
SMN1; SMN2 Q16637 1/20 0.46
PKM P14618 1/20 0.45
LMNA P02545 3/20 0.43
HSD17B2 P37059 2/20 0.43
CYTH2 Q99418 3/20 0.41
EDNRB P24530 3/20 0.40
EDNRA P25101 3/20 0.40
HSD17B1 P14061 1/20 0.39
HPGD P15428 1/20 0.39
HIF1A Q16665 1/20 0.39
HSD17B10 Q99714 1/20 0.39
POLB P06746 1/20 0.39
MAPK1 P28482 1/20 0.39
HTT P42858 1/20 0.39
PTGES O14684 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10913560 0.91 GAA (0.56) GAAALDH1A1TSHRGFERSMN1; SMN2
SCHEMBL21923052 0.81 EDNRB (0.56) GAAALDH1A1TSHRSMN1; SMN2LMNA
SCHEMBL743630 0.81 LMNA (0.65) GAAALDH1A1TSHRGFERSMN1; SMN2
SCHEMBL29727498 0.81 EDNRB (0.56) GAAALDH1A1TSHRSMN1; SMN2LMNA
SCHEMBL2356682 0.80 CYTH2 (0.58) GAAALDH1A1TSHRGFERSMN1; SMN2
SCHEMBL3909224 0.80 GAA (0.53) GAAALDH1A1TSHRGFERSMN1; SMN2
SCHEMBL3950097 0.80 GAA (0.53) GAAALDH1A1TSHRGFERSMN1; SMN2
SCHEMBL7129901 0.79 GAA (0.51) GAAALDH1A1TSHRGFERSMN1; SMN2
SCHEMBL9202081 0.77 ALDH1A1 (0.50) GAAALDH1A1TSHRGFERSMN1; SMN2
SCHEMBL1685394 0.77 BRD4 (0.51) GAAALDH1A1TSHRGFERSMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0565924-B1 Glycoluril powder coating compositions CYTEC TECH CORP (US) 2000-02-02 EP claimed