SCHEMBL7129901

SCHEMBL7129901

Cc1ccc(O)cc1S(=O)(=O)NCl.[Na]

nearest known ligand 0.51

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GAA P10253 5/20 0.51
ALDH1A1 P00352 3/20 0.51
TSHR P16473 2/20 0.51
PKM P14618 1/20 0.49
LMNA P02545 3/20 0.47
GFER P55789 2/20 0.46
SMN1; SMN2 Q16637 1/20 0.46
CYTH2 Q99418 4/20 0.44
HSD17B2 P37059 2/20 0.43
HSD17B1 P14061 1/20 0.42
PTGES O14684 1/20 0.41
POLB P06746 2/20 0.40
IDH1 O75874 1/20 0.40
MEN1 O00255 1/20 0.39
ESR1 P03372 1/20 0.39
KMT2A Q03164 1/20 0.39
ATM Q13315 1/20 0.39
ESR2 Q92731 1/20 0.39
HPGD P15428 1/20 0.39
HIF1A Q16665 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3950097 0.98 GAA (0.53) GAAALDH1A1TSHRPKMLMNA
SCHEMBL10913560 0.83 GAA (0.56) GAAALDH1A1TSHRPKMLMNA
SCHEMBL743630 0.81 LMNA (0.65) GAAALDH1A1TSHRPKMLMNA
SCHEMBL3909224 0.80 GAA (0.53) GAAALDH1A1TSHRPKMLMNA
SCHEMBL8018706 0.79 GAA (0.51) GAAALDH1A1TSHRPKMLMNA
SCHEMBL9202081 0.77 ALDH1A1 (0.50) GAAALDH1A1TSHRPKMLMNA
SCHEMBL1685394 0.77 BRD4 (0.51) GAAALDH1A1TSHRPKMLMNA
SCHEMBL907691 0.77 GAA (0.50) GAAALDH1A1TSHRPKMLMNA
SCHEMBL2356682 0.77 CYTH2 (0.58) GAAALDH1A1TSHRPKMLMNA
SCHEMBL5472657 0.76 MEP1B (0.55) ALDH1A1LMNASMN1; SMN2POLBIDH1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1125497-B1 Product for virucidal disinfection of the hands KESLA FORSCHUNG U SERVICE KG (DE) 2003-06-18 EP disclosed
EP-1125497-A2 Product for virucidal disinfection of the hands Kesla Forschung u. Service KG (DE) 2001-08-22 EP disclosed
EP-0421225-B1 Process for preparing alpha chloro phosphorylidene BASF AG (DE) 1995-04-05 EP disclosed
EP-0421225-A2 Process for preparing alpha chloro phosphorylidene BASF Aktiengesellschaft (DE) 1991-04-10 EP disclosed
EP-0071150-B1 SULFIMINES, THEIR SALTS AND THEIR PREPARATION, AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM Dr. Karl Thomae GmbH (DE) 1985-07-03 EP disclosed
EP-0071150-A1 Sulfimines, their salts and their preparation, and pharmaceutical compositions containing them Dr. Karl Thomae GmbH (DE) 1983-02-09 EP disclosed