SCHEMBL3914904

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL3916138	0.89	PKM (0.39)	ALDH1A1SMN1; SMN2ACHEMAPTTDP1
	SCHEMBL3920596	0.84	ALDH1A1 (0.44)	ALDH1A1SMN1; SMN2ACHEKDM4EMAPT
	SCHEMBL1802615	0.81	ALDH1A1 (0.41)	ALDH1A1ACHEKDM4ETDP1KMT2A
	SCHEMBL1800359	0.78	SIGMAR1 (0.41)	ALDH1A1SMN1; SMN2ACHEKDM4EMAPT
	SCHEMBL1801397	0.78	ACHE (0.39)	ALDH1A1ACHEKDM4EMAPTTDP1
	SCHEMBL1800360	0.77	ALDH1A1 (0.38)	ALDH1A1SMN1; SMN2ACHEKDM4EMAPT
	SCHEMBL1802738	0.77	ALDH1A1 (0.43)	ALDH1A1SMN1; SMN2KDM4EMAPTKMT2A
	SCHEMBL3918144	0.77	MMP2 (0.53)	ALDH1A1SMN1; SMN2KDM4EMAPTKMT2A
	SCHEMBL1802774	0.77	ALDH1A1 (0.46)	ALDH1A1SMN1; SMN2KDM4EMAPTKMT2A
	SCHEMBL1798457	0.77	ALDH1A1 (0.41)	ALDH1A1SMN1; SMN2ACHEKDM4EMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.