SCHEMBL3915181

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL3917724	0.90	CYP2D6 (0.51)	ALDH1A1KDM4EMAPK1TSHRPOLB
	SCHEMBL4035567	0.90	LMNA (0.48)	LMNAALDH1A1KDM4EHSD11B1TSHR
	SCHEMBL3925408	0.89	SMN1; SMN2 (0.48)	LMNAALDH1A1TSHRNR3C1PKM
	SCHEMBL3915453	0.89	HSD11B1 (0.48)	LMNAALDH1A1HSD11B1TSHRSMN1; SMN2
	SCHEMBL3919576	0.88	MMP2 (0.51)	ALDH1A1HSD11B1TSHRNR3C1POLB
	SCHEMBL3918411	0.88	MEN1 (0.49)	LMNAALDH1A1MAPK1TSHRNR3C1
	SCHEMBL3918144	0.85	MMP2 (0.53)	ALDH1A1KDM4ETSHRNR3C1POLB
	SCHEMBL3915497	0.83	CYP2D6 (0.50)	ALDH1A1TSHRPOLBSMN1; SMN2MEN1
	SCHEMBL3925412	0.83	ALDH1A1 (0.46)	LMNAALDH1A1KDM4ETSHRPOLB
	SCHEMBL3917062	0.82	CHRM5 (0.46)	LMNAALDH1A1KDM4EHSD11B1NR3C1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.