Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 1.00 |
| ▸ | KMT2A | Q03164 | 3/20 | 1.00 |
| ▸ | CYP3A4 | P08684 | 2/20 | 1.00 |
| ▸ | TSHR | P16473 | 1/20 | 1.00 |
| ▸ | EDNRA | P25101 | 3/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.51 |
| ▸ | ACLY | P53396 | 1/20 | 0.50 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.48 |
| ▸ | CES1 | P23141 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | IDH1 | O75874 | 2/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12293612 | 0.86 | MEN1 (0.76) | MEN1KMT2ACYP3A4TSHREDNRA | |
| SCHEMBL3912876 | 0.85 | KMT2A (0.73) | MEN1KMT2ACYP3A4TSHREDNRA | |
| SCHEMBL7046426 | 0.76 | MEN1 (0.61) | MEN1KMT2ACYP3A4TSHREDNRA | |
| SCHEMBL12293573 | 0.75 | MAPT (0.64) | MEN1KMT2ACYP3A4TSHREDNRA | |
| SCHEMBL12293620 | 0.75 | MEN1 (0.59) | MEN1KMT2ACYP3A4TSHREDNRA | |
| SCHEMBL11532397 | 0.74 | LMNA (0.62) | MEN1KMT2ACYP3A4TSHREDNRA | |
| SCHEMBL492007 | 0.73 | ACLY (0.77) | MEN1KMT2ACYP3A4TSHRACLY | |
| SCHEMBL1936832 | 0.73 | MEN1 (0.57) | MEN1KMT2ACYP3A4TSHREDNRA | |
| SCHEMBL533130 | 0.72 | PPARG (0.66) | MEN1KMT2ACYP3A4TSHREDNRA | |
| SCHEMBL12293616 | 0.72 | MEN1 (0.57) | MEN1KMT2ACYP3A4TSHREDNRA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090318711-A1 | Non-Covalent Inhibitors of AmpC ß-Lactamase | SHOICHET BRIAN K | 2009-12-24 | — | — | US | disclosed |
| US-7541381-B2 | Non-covalent inhibitors of AmpC β-lactamase | NORTHWESTERN UNIVERSITY (US) | 2009-06-02 | — | — | US | disclosed |
| US-20030232830-A1 | Non-covalent inhibitors of AmpC beta-lactamase | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2003-12-18 | — | — | US | disclosed |
| WO-2003070682-A1 | NON-COVALENT INHIBITORS OF AmpC ß-LACTAMASE | NORTHWESTERN UNIVERSITY (US) | 2003-08-28 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090318711-A1 | Non-Covalent Inhibitors of AmpC ß-Lactamase | AMPD1, AMPD2, AMPD3 | MEN1 4244/4885KMT2A 1451/4885CYP3A4 1243/4885 |
| US-20030232830-A1 | Non-covalent inhibitors of AmpC beta-lactamase | AMPD1, AMPD3, AMPD2 | MEN1 4321/4885KMT2A 1607/4885CYP3A4 1346/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.