Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 3/20 | 0.49 |
| ▸ | CA2 | P00918 | 3/20 | 0.49 |
| ▸ | CA9 | Q16790 | 3/20 | 0.49 |
| ▸ | CA7 | P43166 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
| ▸ | MAPT | P10636 | 2/20 | 0.49 |
| ▸ | HTT | P42858 | 2/20 | 0.49 |
| ▸ | RAB9A | P51151 | 1/20 | 0.49 |
| ▸ | CA12 | O43570 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | ATM | Q13315 | 1/20 | 0.47 |
| ▸ | USP2 | O75604 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2295789 | 0.82 | CA12 (0.66) | CA1CA2CA9ALDH1A1LMNA | |
| SCHEMBL31408148 | 0.81 | LIPE (0.47) | CA1CA2CA9CA7ALDH1A1 | |
| SCHEMBL24251635 | 0.79 | ALDH1A1 (0.59) | ALDH1A1RAB9AMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL13687326 | 0.79 | HTT (0.53) | CA1CA2CA9CA7ALDH1A1 | |
| SCHEMBL15776693 | 0.78 | ALDH1A1 (0.55) | ALDH1A1RAB9AMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL3971804 | 0.78 | RAB9A (0.54) | CA1CA2CA9CA7ALDH1A1 | |
| SCHEMBL5548988 | 0.78 | ALDH1A1 (0.55) | ALDH1A1RAB9AMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL25419509 | 0.78 | ALDH1A1 (0.55) | ALDH1A1RAB9AMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL26357994 | 0.78 | CA12 (0.58) | CA1CA2CA9ALDH1A1LMNA | |
| SCHEMBL12832074 | 0.78 | CA12 (0.54) | CA1CA2CA9ALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2298362-B1 | Responsive paramagnetic MRI contrast agents | BRACCO IMAGING SPA (IT) | 2013-03-13 | — | — | EP | disclosed |
| US-8318134-B2 | Responsive paramagnetic MRI contrast agents | BRACCO IMAGING S.P.A. (IT) | 2012-11-27 | — | — | US | disclosed |
| US-8318134-B2 | Responsive paramagnetic MRI contrast agents | BRACCO IMAGING S.P.A. (IT) | 2012-11-27 | — | — | US | disclosed |
| US-8318134-B2 | Responsive paramagnetic MRI contrast agents | BRACCO IMAGING S.P.A. (IT) | 2012-11-27 | — | — | US | disclosed |
| US-20090234221-A1 | RESPONSIVE PARAMAGNETIC MRI CONTRAST AGENTS | BRACCO IMAGING S.P.A. (IT) | 2009-09-17 | — | — | US | disclosed |
| US-20090234221-A1 | RESPONSIVE PARAMAGNETIC MRI CONTRAST AGENTS | BRACCO IMAGING S.P.A. (IT) | 2009-09-17 | — | — | US | disclosed |
| US-20090234221-A1 | RESPONSIVE PARAMAGNETIC MRI CONTRAST AGENTS | BRACCO IMAGING S.P.A. (IT) | 2009-09-17 | — | — | US | disclosed |
| US-7524483-B2 | Responsive paramagnetic MRI contrast agents | BRACCO IMAGING S.P.A. (IT) | 2009-04-28 | — | — | US | disclosed |
| US-7524483-B2 | Responsive paramagnetic MRI contrast agents | BRACCO IMAGING S.P.A. (IT) | 2009-04-28 | — | — | US | disclosed |
| US-7524483-B2 | Responsive paramagnetic MRI contrast agents | BRACCO IMAGING S.P.A. (IT) | 2009-04-28 | — | — | US | disclosed |
| US-20050191243-A1 | Responsive paramagnetic mri contrast agents | BRACCO IMAGING S.P.A. (IT) | 2005-09-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090234221-A1 | RESPONSIVE PARAMAGNETIC MRI CONTRAST AGENTS | MYT1, PRTN3, CECR2 | CA1 814/4885CA2 982/4885CA9 889/4885 |
| US-20050191243-A1 | Responsive paramagnetic mri contrast agents | MYT1, PRTN3, CECR2 | CA1 814/4885CA2 982/4885CA9 889/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.