Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.52 |
| ▸ | MAPT | P10636 | 4/20 | 0.52 |
| ▸ | LMNA | P02545 | 4/20 | 0.52 |
| ▸ | HPGD | P15428 | 3/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.52 |
| ▸ | POLB | P06746 | 3/20 | 0.52 |
| ▸ | MEN1 | O00255 | 2/20 | 0.52 |
| ▸ | GMNN | O75496 | 2/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.52 |
| ▸ | BLM | P54132 | 2/20 | 0.52 |
| ▸ | PMP22 | Q01453 | 2/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.52 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.52 |
| ▸ | CMKLR1 | Q99788 | 2/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.52 |
| ▸ | TP53 | P04637 | 1/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.52 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.52 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoromethanesulfonic Acid SCHEMBL926342 | 0.86 | ALDH1A1 (0.43) | ALDH1A1MAPTLMNAHPGDKDM4E | |
| SCHEMBL3871190 | 0.83 | PTPN1 (0.56) | ALDH1A1MAPTLMNAHPGDKDM4E | |
| Bromide SCHEMBL4048814 | 0.82 | PTPN1 (0.54) | ALDH1A1MAPTLMNAHPGDKDM4E | |
| SCHEMBL1716864 | 0.74 | ALDH1A1 (0.70) | ALDH1A1MAPTLMNAHPGDKDM4E | |
| SCHEMBL29875679 | 0.74 | ALDH1A1 (0.70) | ALDH1A1MAPTLMNAHPGDKDM4E | |
| SCHEMBL6008188 | 0.74 | ALDH1A1 (0.65) | ALDH1A1MAPTLMNAHPGDKDM4E | |
| SCHEMBL10416279 | 0.74 | ALDH1A1 (0.65) | ALDH1A1MAPTLMNAHPGDKDM4E | |
| SCHEMBL10358075 | 0.73 | ALDH1A1 (0.63) | ALDH1A1MAPTLMNAHPGDKDM4E | |
| SCHEMBL818033 | 0.73 | ALDH1A1 (0.63) | ALDH1A1MAPTLMNAHPGDKDM4E | |
| SCHEMBL6008112 | 0.73 | ALDH1A1 (0.63) | ALDH1A1MAPTLMNAHPGDKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7527913-B2 | Photoacid generators, photoresist composition including the same and method of forming pattern using the same | SAMSUNG ELECTRONICS CO., LTD. (KR) | 2009-05-05 | — | — | US | disclosed |
| US-20080182203-A1 | Photoacid generators, photoresist composition including the same and method of forming pattern using the same | SAMSUNG ELECTRONICS CO., LTD. (KR) | 2008-07-31 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080182203-A1 | Photoacid generators, photoresist composition including the same and method of forming pattern using the same | SUN2, ASIC1, STOM | ALDH1A1 3361/4885MAPT 1726/4885LMNA 4766/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.