Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.53 |
| ▸ | HTT | P42858 | 2/20 | 0.53 |
| ▸ | MEN1 | O00255 | 4/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.50 |
| ▸ | USP2 | O75604 | 1/20 | 0.50 |
| ▸ | NPC1 | O15118 | 2/20 | 0.49 |
| ▸ | RAB9A | P51151 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | POLB | P06746 | 2/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | MAOB | P27338 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | THRB | P10828 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3921265 | 0.87 | ALDH1A1 (0.60) | MAPTHTTMEN1KMT2ANPC1 | |
| SCHEMBL3915221 | 0.86 | HTT (0.72) | MAPTHTTMEN1KMT2ANPC1 | |
| SCHEMBL3922167 | 0.84 | MEN1 (0.47) | MAPTHTTMEN1KMT2ANPC1 | |
| SCHEMBL29798065 | 0.78 | HTT (0.56) | MAPTHTTMEN1KMT2AUSP2 | |
| SCHEMBL3914469 | 0.77 | MAPT (0.55) | MAPTHTTMEN1KMT2AUSP2 | |
| SCHEMBL3923245 | 0.76 | HTT (0.52) | MAPTHTTMEN1KMT2ANPC1 | |
| SCHEMBL3915867 | 0.73 | TDP1 (0.60) | MAPTHTTMEN1KMT2APOLB | |
| SCHEMBL3924129 | 0.72 | ABL1 (0.63) | MAPTMEN1KMT2ANPC1RAB9A | |
| SCHEMBL3916029 | 0.72 | LMNA (0.60) | MAPTHTTMEN1KMT2ANPC1 | |
| SCHEMBL3913448 | 0.71 | MAPT (0.58) | MAPTMEN1KMT2ARAB9AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060270720-A1 | Iminothiazolidinone derivatives as SFRP-1 antagonists | WYETH (US) | 2006-11-30 | — | — | US | claimed |
| US-7563813-B2 | Iminothiazolidinone derivatives as SFRP-1 antagonists | WYETH (US) | 2009-07-21 | — | — | US | disclosed |
| US-20060270720-A1 | Iminothiazolidinone derivatives as SFRP-1 antagonists | WYETH (US) | 2006-11-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060270720-A1 | Iminothiazolidinone derivatives as SFRP-1 antagonists | SFRP1, FZD7, DKK1 | MAPT 3137/4885HTT 4604/4885MEN1 356/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.