Sugi Predict

Sugi Predict / Compounds / Cyclohexane

Cyclohexane

Cyclohexane

SCHEMBL392262

C1CCCCC1.CCOC(=O)CCC(=O)O

nearest known ligand 0.55

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ LMNA P02545 3/20 0.55
▸ CYP1A2 P05177 1/20 0.48
▸ MGAM O43451 1/20 0.48
▸ GAA P10253 1/20 0.48
▸ SI P14410 1/20 0.48
▸ MGAM2 Q2M2H8 1/20 0.48
▸ TSHR P16473 2/20 0.46
▸ POLB P06746 1/20 0.46
▸ EGLN1 Q9GZT9 2/20 0.45
▸ KDM6B O15054 1/20 0.45
▸ KDM5C P41229 1/20 0.45
▸ PHF8 Q9UPP1 1/20 0.45
▸ KDM2A Q9Y2K7 1/20 0.45
▸ ALDH1A1 P00352 4/20 0.44
▸ TRPA1 O75762 1/20 0.44
▸ SMN1; SMN2 Q16637 1/20 0.43
▸ ALKBH5 Q6P6C2 1/20 0.41
▸ SUCNR1 Q9BXA5 1/20 0.41
▸ FFAR3 O14843 2/20 0.40
▸ HDAC3 O15379 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Cyclopropane SCHEMBL10940609 1.00 LMNA (0.55) LMNACYP1A2MGAMGAASI
SCHEMBL363334 0.93 MGAM (0.55) LMNACYP1A2MGAMGAASI
SCHEMBL262913 0.93 MGAM (0.55) LMNACYP1A2MGAMGAASI
Succinic Acid Diethyl Ester SCHEMBL27830938 0.93 MGAM (0.55) LMNACYP1A2MGAMGAASI
Succinic Acid Diethyl Ester SCHEMBL27966388 0.93 MGAM (0.55) LMNACYP1A2MGAMGAASI
Methyl Alcohol SCHEMBL2707570 0.91 MGAM (0.52) LMNACYP1A2MGAMGAASI
Water SCHEMBL1110192 0.91 MGAM (0.52) LMNACYP1A2MGAMGAASI
SCHEMBL818402 0.91 MGAM (0.52) LMNACYP1A2MGAMGAASI
Hydrochloric Acid SCHEMBL1006465 0.91 MGAM (0.52) LMNACYP1A2MGAMGAASI
Methyl Alcohol SCHEMBL6759312 0.91 MGAM (0.52) LMNACYP1A2MGAMGAASI

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 82 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-108627582-A A kind of Fructus Aristolochiae Kwangsiensis drug for analgesic 贵州景诚制药有限公司 2018-10-09 — — CN claimed
US-10667993-B2 Polymerizable compositions based on thermally cleavable compounds IVOCLAR VIVADENT AG (LI) 2020-06-02 — — US disclosed
CN-108627582-A A kind of Fructus Aristolochiae Kwangsiensis drug for analgesic 贵州景诚制药有限公司 2018-10-09 — — CN disclosed
US-20180200155-A1 Polymerizable Compositions Based On Thermally Cleavable Compounds IVOCLAR VIVADENT AG (LI) 2018-07-19 — — US disclosed
EP-2906539-B1 INHIBITORS OF VIRAL REPLICATION, THEIR PROCESS OF PREPARATION AND THEIR THERAPEUTICAL USES HIVIH (FR) 2017-06-21 — — EP disclosed
US-9475802-B2 Inhibitors of viral replication, their process of preparation and their therapeutical uses LABORATOIRE BIODIM (FR) 2016-10-25 — — US disclosed
EP-2886531-B1 Aspartic acid derivatives MERCK PATENT GMBH (DE) 2016-06-08 — — EP disclosed
US-20150274718-A1 Inhibitors of Viral Replication, Their Process of Preparation and Their Therapeutical Uses LABORATOIRE BIODIM (FR) 2015-10-01 — — US disclosed
EP-2906539-A1 INHIBITORS OF VIRAL REPLICATION, THEIR PROCESS OF PREPARATION AND THEIR THERAPEUTICAL USES LABORATOIRE BIODIM (FR) 2015-08-19 — — EP disclosed
EP-2886531-A1 Aspartic acid derivatives Merck Patent GmbH (DE) 2015-06-24 — — EP disclosed
US-4180672-A 2-Organothio-2-cyclopentenones, organothio-cyclopentanes derived therefrom TEIJIN LIMITED (JP) 1979-12-25 — — US disclosed
US-4179575-A CYCLOPROPANECARBOXYLIC ACIDS, PESTICIDES ROUSSEL UCLAF (FR) 1979-12-18 — — US disclosed
US-4178461-A BRONCHODILATORS, GASTRIC ACID SECRETION INHIBITORS AMERICAN CYANAMID COMPANY (US) 1979-12-11 — — US disclosed
US-4054604-A MICROBIOCIDES, HYPOTENSIVE AGENTS AMERICAN CYANAMID COMPANY (US) 1977-10-18 — — US disclosed
US-4045577-A 15-PROPIONYLOXY-9-OXO-5,13 PROSTADIENOIC ACID, ANTIHYPERTENSIVE AGENTS ALZA CORPORATION (US) 1977-08-30 — — US disclosed
US-4044043-A HYPERTENSIVE AGENTS, MICROBIOCIDES AMERICAN CYANAMID COMPANY (US) 1977-08-23 — — US disclosed
US-4028396-A BRONCHODILATORS, GASTRIC ACID SECRETION INHIBITORS AMERICAN CYANAMID COMPANY (US) 1977-06-07 — — US disclosed
US-3994865-A MELT SPINNING CIBA-GEIGY CORPORATION (US) 1976-11-30 — — US disclosed
US-3981868-A MICROBIOCIDES, HYPOTENSIVE AGENTS AMERICAN CYANAMID COMPANY (US) 1976-09-21 — — US disclosed
US-3975413-A Novel haptenes and antigens PIERDET ANDRE 1976-08-17 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20180200155-A1 Polymerizable Compositions Based On Thermally Cleavable Compounds CAD, TERB1, MLX LMNA 157/4885CYP1A2 2458/4885MGAM 2817/4885
US-10667993-B2 Polymerizable compositions based on thermally cleavable compounds CAD, TERB1, MLX LMNA 157/4885CYP1A2 2458/4885MGAM 2817/4885
US-20150274718-A1 Inhibitors of Viral Replication, Their Process of Preparation and Their Therapeutical Uses RPL35, EIF2AK2, MAVS LMNA 1718/4885CYP1A2 2862/4885MGAM 1313/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.