Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE known ✓ | P22303 | 2/20 | 0.32 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | BCHE | P06276 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | MAOB | P27338 | 1/20 | 0.30 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL2259028 | 0.91 | RAB9A (0.38) | RAB9AALDH1A1KDM4EACHEBCHE | |
| Hydrochloric Acid SCHEMBL2259575 | 0.83 | RAB9A (0.45) | RAB9AALDH1A1KDM4EACHEBCHE | |
| Hydrochloric Acid SCHEMBL2264053 | 0.82 | ALDH1A1 (0.36) | RAB9AALDH1A1KDM4EACHEBCHE | |
| Hydrochloric Acid SCHEMBL2892896 | 0.82 | RAB9A (0.38) | RAB9AALDH1A1KDM4EACHEBCHE | |
| Trifluoromethanesulfonamide SCHEMBL3260193 | 0.80 | LMNA (0.32) | RAB9ALMNAHTTSMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL2260155 | 0.79 | ALDH1A1 (0.51) | RAB9AALDH1A1KDM4ELMNAHTT | |
| Hydrochloric Acid SCHEMBL2258374 | 0.79 | ACP3 (0.39) | ALDH1A1BCHESMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL3921996 | 0.78 | POLB (0.31) | RAB9AALDH1A1KDM4EACHEBCHE | |
| Hydrochloric Acid SCHEMBL3919637 | 0.77 | KDM4E (0.34) | RAB9AALDH1A1KDM4E | |
| Hydrochloric Acid SCHEMBL604178 | 0.77 | FDPS (0.33) | RAB9AALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060110638-A1 | Electrochromic compounds | NTERA LIMITED (IE) | 2006-05-25 | — | — | US | claimed |
| EP-1443091-A1 | Electrochromic compounds | Ntera Limited (IE) | 2004-08-04 | — | — | EP | claimed |
| US-20090259042-A1 | ELECTROCHROMIC COMPOUNDS | NTERA LIMITED (IE) | 2009-10-15 | — | — | US | disclosed |
| US-7567371-B2 | Electrochromic compounds | NTERA LIMITED (IE) | 2009-07-28 | — | — | US | disclosed |
| US-20060110638-A1 | Electrochromic compounds | NTERA LIMITED (IE) | 2006-05-25 | — | — | US | disclosed |
| EP-1443091-A1 | Electrochromic compounds | Ntera Limited (IE) | 2004-08-04 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090259042-A1 | ELECTROCHROMIC COMPOUNDS | ETV6, HCN2, EED | ACHE 161/4885RAB9A 654/4885ALDH1A1 1280/4885 |
| US-20060110638-A1 | Electrochromic compounds | ETV6, HCN2, EED | ACHE 161/4885RAB9A 654/4885ALDH1A1 1280/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.