Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | MMP1 | P03956 | 1/20 | 0.39 |
| ▸ | MMP2 | P08253 | 1/20 | 0.39 |
| ▸ | MMP3 | P08254 | 1/20 | 0.39 |
| ▸ | MMP7 | P09237 | 1/20 | 0.39 |
| ▸ | MMP9 | P14780 | 1/20 | 0.39 |
| ▸ | MMP8 | P22894 | 1/20 | 0.39 |
| ▸ | MMP13 | P45452 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.39 |
| ▸ | LTA4H | P09960 | 1/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5660242 | 0.90 | YAP1 (0.42) | MEN1KMT2ALMNAALDH1A1MAPT | |
| SCHEMBL3922996 | 0.84 | LTA4H (0.38) | MEN1KMT2ALMNAALDH1A1RAB9A | |
| SCHEMBL2246968 | 0.82 | NPC1 (0.41) | LMNARAB9ANPC1TP53TYK2 | |
| SCHEMBL5660237 | 0.81 | ALOX5 (0.36) | MEN1KMT2ALMNAALDH1A1RAB9A | |
| SCHEMBL2245019 | 0.78 | NPC1 (0.47) | KMT2ALMNARAB9ANPC1TP53 | |
| SCHEMBL13248365 | 0.78 | MEN1 (0.56) | MEN1KMT2ALMNARAB9ANPC1 | |
| SCHEMBL2248325 | 0.76 | NPC1 (0.39) | LMNARAB9ANPC1TP53TYK2 | |
| SCHEMBL2246935 | 0.76 | NPC1 (0.39) | LMNARAB9ANPC1TP53TYK2 | |
| SCHEMBL13248366 | 0.76 | NPSR1 (0.45) | MEN1KMT2ALMNARAB9ANPC1 | |
| SCHEMBL2996834 | 0.74 | ADAMTS4 (0.46) | MEN1KMT2ALMNAALDH1A1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1814877-B1 | DIPHENYL SUBSTITUTED ALKANES AS FLAP INHIBITORS | MERCK & CO INC (US) | 2009-03-11 | — | — | EP | disclosed |