SCHEMBL3924733

SCHEMBL3924733

C[Si](CBr)(Oc1ccccc1)Oc1ccccc1

nearest known ligand 0.39

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
CA4 P22748 1/20 0.39
LTA4H P09960 4/20 0.36
TSHR P16473 2/20 0.36
KCNA3 P22001 1/20 0.36
HTR1B P28222 2/20 0.33
ALDH1A1 P00352 2/20 0.33
KCNH2 Q12809 2/20 0.33
TRPA1 O75762 1/20 0.33
LMNA P02545 1/20 0.33
HTR1D P28221 1/20 0.33
TDP1 Q9NUW8 1/20 0.32
TAAR1 Q96RJ0 1/20 0.32
RECQL P46063 1/20 0.32
CHRNB2 P17787 1/20 0.31
CHRNB4 P30926 1/20 0.31
CHRNA3 P32297 1/20 0.31
CHRNA7 P36544 1/20 0.31
CHRNA4 P43681 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3914259 0.82 CA4 (0.39) CA4LTA4HTSHRKCNA3HTR1B
SCHEMBL705837 0.81 CA4 (0.42) CA4LTA4HTSHRKCNA3HTR1B
SCHEMBL704601 0.81 CA4 (0.42) CA4LTA4HTSHRKCNA3HTR1B
SCHEMBL3917624 0.79 KCNA3 (0.35) CA4LTA4HTSHRKCNA3HTR1B
SCHEMBL1609541 0.79 LTA4H (0.40) CA4LTA4HTSHRKCNA3HTR1B
SCHEMBL705384 0.77 KCNA3 (0.41) CA4LTA4HTSHRKCNA3HTR1B
SCHEMBL3924741 0.77 LTA4H (0.42) CA4LTA4HTSHRKCNA3ALDH1A1
SCHEMBL704371 0.77 KCNA3 (0.41) CA4LTA4HTSHRKCNA3HTR1B
SCHEMBL13089259 0.77 CA4 (0.39) CA4LTA4HTSHRKCNA3HTR1B
SCHEMBL3916371 0.76 LTA4H (0.39) CA4LTA4HTSHRKCNA3ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7619108-B2 Process for preparing unsaturated organosilicon compounds WACKER CHEMIE AG (DE) 2009-11-17 US disclosed
EP-1954701-B1 PROCESS FOR PREPARING UNSATURATED ORGANOSILICON COMPOUNDS WACKER CHEMIE AG (DE) 2009-03-18 EP disclosed
US-20080293958-A1 Process for Preparing Unsaturated Organosilicon Compounds WACKER CHEMIE AG (DE) 2008-11-27 US disclosed
US-6815554-B2 REACTING A HALOALKYLSILANE WITH A SALT OF AN UNSATURATED CARBOXYLIC ACID IN THE PRESENCE OF A PHASE TRANSFER CATALYST; BONDING AGENTS WACKER-CHEMIE GMBH (DE) 2004-11-09 US disclosed
US-20020151736-A1 PROCESS FOR PREPARING UNSATURATED ORGANOSILICON COMPOUNDS WACKER-CHEMIE GMBH (DE) 2002-10-17 US disclosed