SCHEMBL3924741

SCHEMBL3924741

C[Si](CCl)(Oc1ccccc1)Oc1ccccc1

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LTA4H P09960 6/20 0.42
TSHR P16473 1/20 0.42
CA4 P22748 1/20 0.39
NR1H2 P55055 1/20 0.38
BAX Q07812 1/20 0.38
RNF4 P78317 1/20 0.38
LMNA P02545 1/20 0.38
TTR P02766 1/20 0.37
ALDH1A1 P00352 2/20 0.37
RECQL P46063 1/20 0.37
PAX8 Q06710 1/20 0.36
KCNA3 P22001 1/20 0.36
ALOX15 P16050 1/20 0.35
MAPT P10636 1/20 0.35
MITF O75030 1/20 0.35
POLB P06746 1/20 0.35
MAPK1 P28482 1/20 0.35
HTT P42858 1/20 0.35
CA5A P35218 1/20 0.34
CA5B Q9Y2D0 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3914716 0.82 CA4 (0.39) LTA4HTSHRCA4LMNATTR
SCHEMBL705837 0.81 CA4 (0.42) LTA4HTSHRCA4LMNAALDH1A1
SCHEMBL704601 0.81 CA4 (0.42) LTA4HTSHRCA4LMNAALDH1A1
SCHEMBL3923262 0.79 KCNA3 (0.40) LTA4HTSHRCA4LMNAALDH1A1
SCHEMBL1609541 0.79 LTA4H (0.40) LTA4HTSHRCA4LMNAALDH1A1
SCHEMBL705384 0.77 KCNA3 (0.41) LTA4HTSHRCA4LMNARECQL
SCHEMBL3924733 0.77 CA4 (0.39) LTA4HTSHRCA4LMNAALDH1A1
SCHEMBL13089259 0.77 CA4 (0.39) LTA4HTSHRCA4LMNAALDH1A1
SCHEMBL704371 0.77 KCNA3 (0.41) LTA4HTSHRCA4LMNARECQL
SCHEMBL3915000 0.76 LTA4H (0.39) LTA4HTSHRCA4RNF4TTR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7619108-B2 Process for preparing unsaturated organosilicon compounds WACKER CHEMIE AG (DE) 2009-11-17 US disclosed
EP-1954701-B1 PROCESS FOR PREPARING UNSATURATED ORGANOSILICON COMPOUNDS WACKER CHEMIE AG (DE) 2009-03-18 EP disclosed
US-20080293958-A1 Process for Preparing Unsaturated Organosilicon Compounds WACKER CHEMIE AG (DE) 2008-11-27 US disclosed
US-6815554-B2 REACTING A HALOALKYLSILANE WITH A SALT OF AN UNSATURATED CARBOXYLIC ACID IN THE PRESENCE OF A PHASE TRANSFER CATALYST; BONDING AGENTS WACKER-CHEMIE GMBH (DE) 2004-11-09 US disclosed
US-20020151736-A1 PROCESS FOR PREPARING UNSATURATED ORGANOSILICON COMPOUNDS WACKER-CHEMIE GMBH (DE) 2002-10-17 US disclosed
EP-1249454-A1 Preparation of unsaturated organo-silicon compounds Wacker-Chemie GmbH (DE) 2002-10-16 EP disclosed