Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8966216 | 0.81 | THRB (0.42) | TSHR | |
| SCHEMBL8966752 | 0.79 | ADRB2 (0.39) | TSHR | |
| SCHEMBL15312386 | 0.77 | THRB (0.42) | TSHR | |
| SCHEMBL4274113 | 0.76 | ANPEP (0.41) | TSHR | |
| SCHEMBL28191740 | 0.74 | TSHR (0.44) | TSHR | |
| SCHEMBL29237155 | 0.74 | TSHR (0.54) | TSHR | |
| SCHEMBL181158 | 0.73 | TSHR (0.77) | TSHR | |
| Octane SCHEMBL6002112 | 0.73 | TSHR (0.77) | TSHR | |
| Palmitonitrile SCHEMBL17183997 | 0.73 | TSHR (0.77) | TSHR | |
| SCHEMBL11095447 | 0.73 | TSHR (0.77) | TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090286995-A1 | METHOD FOR THE PRODUCTION OF BORONIC ACIDS CARRYING CYANOALKYL, CARBOXYL AND AMINOCARBONYL GROUPS AND THEIR DERIVATIVES | ARCHIMICA GMBH (DE) | 2009-11-19 | — | — | US | disclosed |
| EP-2013220-A1 | METHOD FOR THE PRODUCTION OF BORONIC ACIDS CARRYING CYANOALKYL, CARBOXYL AND AMINOCARBONYL GROUPS AND THEIR DERIVATIVES | Archimica GmbH (DE) | 2009-01-14 | — | — | EP | disclosed |
| WO-2007121805-A1 | METHOD FOR THE PRODUCTION OF BORONIC ACIDS CARRYING CYANOALKYL, CARBOXYL AND AMINOCARBONYL GROUPS AND THEIR DERIVATIVES | ARCHIMICA GMBH (DE) | 2007-11-01 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090286995-A1 | METHOD FOR THE PRODUCTION OF BORONIC ACIDS CARRYING CYANOALKYL, CARBOXYL AND AMINOCARBONYL GROUPS AND THEIR DERIVATIVES | BCAT1, BCAT2, SLC1A5 | TSHR 2512/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.