SCHEMBL3925075

SCHEMBL3925075

CC(C)c1ccc(S(N)(=O)=O)c(C(C)C)c1C(C)C

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA1 P00915 7/20 0.39
CA2 P00918 7/20 0.39
CA9 Q16790 6/20 0.39
CA12 O43570 5/20 0.39
ALDH1A1 P00352 3/20 0.34
CA4 P22748 3/20 0.33
CA6 P23280 3/20 0.33
CA5A P35218 3/20 0.33
CA7 P43166 3/20 0.33
CA5B Q9Y2D0 3/20 0.33
SLC9A1 P19634 2/20 0.33
CA14 Q9ULX7 2/20 0.33
LDHA P00338 1/20 0.33
SLC9A2 Q9UBY0 1/20 0.33
ACHE P22303 1/20 0.33
CYP2C9 P11712 1/20 0.33
KDM4E B2RXH2 1/20 0.32
PDIA6 Q15084 1/20 0.32
L3MBTL1 Q9Y468 1/20 0.32
CA3 P07451 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5327127 0.82 CA2 (0.45) CA1CA2CA9CA12CA4
SCHEMBL971368 0.82 L3MBTL1 (0.32) ALDH1A1SLC9A1SLC9A2L3MBTL1
SCHEMBL10980384 0.80 L3MBTL1 (0.32) ALDH1A1SLC9A1SLC9A2L3MBTL1
SCHEMBL719443 0.80 FABP3 (0.41) CA1CA2CA9ALDH1A1CA7
SCHEMBL216708 0.80 TRPV4 (0.38) ALDH1A1SLC9A1SLC9A2L3MBTL1
SCHEMBL30010765 0.80 TRPV4 (0.38) ALDH1A1SLC9A1SLC9A2L3MBTL1
SCHEMBL9425114 0.79 SLC9A1 (0.31) SLC9A1SLC9A2
SCHEMBL3550344 0.79 ACHE (0.47) ALDH1A1SLC9A1SLC9A2ACHEKDM4E
SCHEMBL11793665 0.79 CA1 (0.33) CA1CA2CA9CA12CA4
SCHEMBL10435622 0.78 L3MBTL1 (0.31) CA1CA2CA9CA7L3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4313305-A1 SARS-COV-2 MPRO INHIBITOR COMPOUNDS Heptares Therapeutics Limited (GB) 2024-02-07 EP disclosed
CN-117186109-A Tetrazine nitrate imitation compound and preparation method thereof 北京理工大学 2023-12-08 CN disclosed
US-8084448-B2 Organic compounds NOVARTIS AG (CH) 2011-12-27 US disclosed
US-20090181928-A1 ORGANIC COMPOUNDS NOVARTIS AG (CH) 2009-07-16 US disclosed
EP-2038267-A2 THIADIAZOLIDINONE INHIBITORS OF PTPASE Novartis AG (CH) 2009-03-25 EP disclosed
WO-2007115058-A2 THIADIAZOLIDINONE INHIBITORS OF PTPASE NOVARTIS AG (CH) 2007-10-11 WO disclosed
WO-2004080389-A2 HYDROXYEICOSADIENAMIDE COMPOUNDS TAISHO PHARMACEUTICAL CO., LTD. (JP) 2004-09-23 WO disclosed
EP-0939629-A4 THIOL SULFONAMIDE METALLOPROTEASE INHIBITORS MONSANTO CO (US) 2002-07-17 EP disclosed
EP-0939629-A1 THIOL SULFONAMIDE METALLOPROTEASE INHIBITORS MONSANTO COMPANY (US) 1999-09-08 EP disclosed
WO-1998003166-A1 THIOL SULFONAMIDE METALLOPROTEASE INHIBITORS MONSANTO COMPANY (US) 1998-01-29 WO disclosed
EP-0299533-B1 HIGH POTENCY SWEETENING AGENTS THE NUTRASWEET COMPANY (a Delaware corporation) (US) 1993-04-07 EP disclosed
WO-1989000563-A1 HIGH POTENCY SWEETENING AGENTS THE NUTRASWEET COMPANY (US) 1989-01-26 WO disclosed
EP-0299533-A2 High potency sweetening agents THE NUTRASWEET COMPANY (a Delaware corporation) (US) 1989-01-18 EP disclosed
EP-0069585-B1 COLOR-FORMING SULFONAMIDODIPHENYLAMINES, PHOTOGRAPHIC ELEMENTS CONTAINING THEM AND CORRESPONDING SULFONIMIDE DYES EASTMAN KODAK COMPANY (a New Jersey corporation) (US) 1985-07-03 EP disclosed
US-4499304-A COLOR PHOTOGRAPHY;SILVER HALIDE EMULSIONS; PRINTING PLATES; IMAGES EASTMAN KODAK COMPANY (US) 1985-02-12 US disclosed
EP-0069585-A1 Color-forming sulfonamidodiphenylamines, photographic elements containing them and corresponding sulfonimide dyes EASTMAN KODAK COMPANY (a New Jersey corporation) (US) 1983-01-12 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090181928-A1 ORGANIC COMPOUNDS PTPRS, PTPRO, PTPRC CA1 4094/4885CA2 1736/4885CA9 2368/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.