Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BLM | P54132 | 2/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | SLC1A1 | P43005 | 3/20 | 0.41 |
| ▸ | GRIK1 | P39086 | 3/20 | 0.41 |
| ▸ | GRIN1 | Q05586 | 2/20 | 0.41 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.41 |
| ▸ | GRIK2 | Q13002 | 2/20 | 0.41 |
| ▸ | SLC1A2 | P43004 | 2/20 | 0.41 |
| ▸ | GRM8 | O00222 | 1/20 | 0.41 |
| ▸ | GRM6 | O15303 | 1/20 | 0.41 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.41 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.41 |
| ▸ | GSR | P00390 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | GRM5 | P41594 | 1/20 | 0.41 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.41 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.41 |
| ▸ | GRIA3 | P42263 | 1/20 | 0.41 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.41 |
| ▸ | GRIA4 | P48058 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3926153 | 0.88 | LMNA (0.45) | BLMLMNAGRIN1GRIN2BNAAA | |
| SCHEMBL3448590 | 0.86 | SLC1A1 (0.50) | BLMSLC1A1GRIK1GRIN1GRIN2B | |
| SCHEMBL9503510 | 0.83 | NAAA (0.47) | BLMSLC1A1GRIK1GRIN1GRIN2B | |
| SCHEMBL1845737 | 0.81 | NAAA (0.49) | BLMLMNASLC1A1GRIK1GRIN1 | |
| SCHEMBL18071166 | 0.81 | NAAA (0.49) | BLMLMNASLC1A1GRIK1GRIN1 | |
| SCHEMBL8647815 | 0.77 | BLM (0.45) | BLMLMNAGRIN1GRIN2BALOX15 | |
| SCHEMBL7370717 | 0.76 | LMNA (0.36) | BLMLMNANAAA | |
| SCHEMBL8059341 | 0.76 | NAAA (0.50) | NAAAALDH1A1 | |
| SCHEMBL7373342 | 0.76 | LMNA (0.38) | BLMLMNAGRIK1GRIK2NAAA | |
| SCHEMBL7375190 | 0.73 | LMNA (0.34) | BLMLMNANAAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1940376-A2 | USE OF NEBOGLAMINE IN THE TREATMENT OF TOXICODEPENDENCY | ROTTAPHARM S.P.A. (IT) | 2008-07-09 | — | — | EP | claimed |
| WO-2007039869-A2 | USE OF NEBOGLAMINE IN THE TREATMENT OF TOXICODEPENDENCY | ROTTAPHARM S.P.A. (IT) | 2007-04-12 | — | — | WO | claimed |
| EP-1940376-B1 | USE OF NEBOGLAMINE IN THE TREATMENT OF TOXICODEPENDENCY | ROTTAPHARM SPA (IT) | 2009-03-18 | — | — | EP | disclosed |
| EP-1940376-A2 | USE OF NEBOGLAMINE IN THE TREATMENT OF TOXICODEPENDENCY | ROTTAPHARM S.P.A. (IT) | 2008-07-09 | — | — | EP | disclosed |
| WO-2007039869-A3 | USE OF NEBOGLAMINE IN THE TREATMENT OF TOXICODEPENDENCY | ROTTAPHARM SPA (IT) | 2007-07-05 | — | — | WO | disclosed |
| WO-2007039869-A2 | USE OF NEBOGLAMINE IN THE TREATMENT OF TOXICODEPENDENCY | ROTTAPHARM S.P.A. (IT) | 2007-04-12 | — | — | WO | disclosed |