Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | BLM | P54132 | 1/20 | 0.34 |
| ▸ | NAAA | Q02083 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7370717 | 0.86 | LMNA (0.36) | LMNABLMNAAA | |
| SCHEMBL3926151 | 0.73 | BLM (0.48) | LMNABLMNAAA | |
| SCHEMBL3926153 | 0.73 | LMNA (0.45) | LMNABLMNAAA | |
| SCHEMBL8059341 | 0.70 | NAAA (0.50) | NAAA | |
| SCHEMBL27917893 | 0.70 | NAAA (0.42) | LMNABLMNAAA | |
| SCHEMBL7373342 | 0.70 | LMNA (0.38) | LMNABLMNAAA | |
| SCHEMBL27616995 | 0.68 | CYP2C19 (0.40) | LMNABLMNAAA | |
| SCHEMBL24158545 | 0.68 | KMT2A (0.39) | BLM | |
| SCHEMBL19955094 | 0.68 | KMT2A (0.39) | BLM | |
| SCHEMBL20954557 | 0.67 | MGAM (0.40) | LMNABLMNAAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0688312-B1 | NEW DERIVATIVES OF GLUTAMIC ACID, A METHOD OF PREPARING THEM, AND THEIR USE AS DRUGS FOR ENHANCING MEMORY AND LEARNING | ROTTA RESEARCH LAB (IT) | 1998-11-18 | — | — | EP | disclosed |
| US-5723494-A | Derivatives of glutamic and aspartic acids, a method of preparing them, and their use as drugs for enhancing memory and learning | ROTTA RESEARCH LABORATORIUM S.P.A. (IT) | 1998-03-03 | — | — | US | disclosed |
| EP-0688312-A1 | NEW DERIVATIVES OF GLUTAMIC ACID, A METHOD OF PREPARING THEM, AND THEIR USE AS DRUGS FOR ENHANCING MEMORY AND LEARNING | ROTTA RESEARCH LABORATORIUM S.P.A. (IT) | 1995-12-27 | — | — | EP | disclosed |
| WO-1994020454-A1 | NEW DERIVATIVES OF GLUTAMIC AND ASPARTIC ACIDS, A METHOD OF PREPARING THEM, AND THEIR USE AS DRUGS FOR ENHANCING MEMORY AND LEARNING | ROTTA RESEARCH LABORATORIUM S.P.A. (IT) | 1994-09-15 | — | — | WO | disclosed |