Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | BLM | P54132 | 1/20 | 0.36 |
| ▸ | NAAA | Q02083 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | GPBAR1 | Q8TDU6 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7375190 | 0.86 | LMNA (0.34) | LMNABLMNAAA | |
| SCHEMBL3926153 | 0.76 | LMNA (0.45) | LMNABLMNAAASMN1; SMN2CYP2C19 | |
| SCHEMBL3926151 | 0.76 | BLM (0.48) | LMNABLMNAAA | |
| SCHEMBL27917893 | 0.73 | NAAA (0.42) | LMNABLMNAAASMN1; SMN2CYP2C19 | |
| SCHEMBL8059341 | 0.73 | NAAA (0.50) | NAAASMN1; SMN2CYP2C19 | |
| SCHEMBL7373342 | 0.73 | LMNA (0.38) | LMNABLMNAAACYP2C19 | |
| SCHEMBL27616995 | 0.71 | CYP2C19 (0.40) | LMNABLMNAAACYP2C19 | |
| SCHEMBL20954557 | 0.70 | MGAM (0.40) | LMNABLMNAAACYP2C19 | |
| SCHEMBL16838363 | 0.69 | NAAA (0.41) | LMNABLMNAAACYP2C19 | |
| SCHEMBL13232254 | 0.69 | ATM (0.42) | LMNABLMSMN1; SMN2CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0688312-B1 | NEW DERIVATIVES OF GLUTAMIC ACID, A METHOD OF PREPARING THEM, AND THEIR USE AS DRUGS FOR ENHANCING MEMORY AND LEARNING | ROTTA RESEARCH LAB (IT) | 1998-11-18 | — | — | EP | disclosed |
| US-5723494-A | Derivatives of glutamic and aspartic acids, a method of preparing them, and their use as drugs for enhancing memory and learning | ROTTA RESEARCH LABORATORIUM S.P.A. (IT) | 1998-03-03 | — | — | US | disclosed |
| EP-0688312-A1 | NEW DERIVATIVES OF GLUTAMIC ACID, A METHOD OF PREPARING THEM, AND THEIR USE AS DRUGS FOR ENHANCING MEMORY AND LEARNING | ROTTA RESEARCH LABORATORIUM S.P.A. (IT) | 1995-12-27 | — | — | EP | disclosed |
| WO-1994020454-A1 | NEW DERIVATIVES OF GLUTAMIC AND ASPARTIC ACIDS, A METHOD OF PREPARING THEM, AND THEIR USE AS DRUGS FOR ENHANCING MEMORY AND LEARNING | ROTTA RESEARCH LABORATORIUM S.P.A. (IT) | 1994-09-15 | — | — | WO | disclosed |