Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.56 |
| ▸ | GRM5 | P41594 | 3/20 | 0.38 |
| ▸ | PRKDC | P78527 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.32 |
| ▸ | CDK4 | P11802 | 1/20 | 0.32 |
| ▸ | CDK2 | P24941 | 1/20 | 0.32 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.32 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.32 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | GLA | P06280 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | PKM | P14618 | 2/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL163828 | 0.76 | NPC1 (0.42) | ADORA3KDM4ESMN1; SMN2KMT2AALDH1A1 | |
| SCHEMBL174735 | 0.75 | ADORA3 (1.00) | ADORA3GRM5PRKDCKDM4EADORA2A | |
| Hydrochloric Acid SCHEMBL5127992 | 0.73 | ADORA3 (0.96) | ADORA3GRM5PRKDCKDM4EADORA2A | |
| Hydrochloric Acid SCHEMBL5129999 | 0.73 | ADORA3 (0.96) | ADORA3GRM5PRKDCKDM4EADORA2A | |
| Hydrochloric Acid SCHEMBL10598992 | 0.73 | ADORA3 (0.96) | ADORA3GRM5PRKDCKDM4EADORA2A | |
| Trifluoroacetic Acid SCHEMBL5132448 | 0.64 | ADORA3 (0.73) | ADORA3GRM5KDM4ECDK4CDK2 | |
| SCHEMBL13256676 | 0.64 | KDM4E (0.67) | ADORA3KDM4EADORA2AADORA2BADORA1 | |
| SCHEMBL20602860 | 0.64 | ADORA3 (0.61) | ADORA3GRM5PRKDCKDM4EADORA2A | |
| SCHEMBL3326263 | 0.62 | ADORA3 (0.71) | ADORA3GRM5PRKDCKDM4EADORA2A | |
| SCHEMBL862066 | 0.62 | KDM4E (0.51) | ADORA3GRM5PRKDCKDM4EADORA2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7541465-B2 | Substituted 2-aminoacetamides and the use thereof | PURDUE NEUROSCIENCE COMPANY (US) | 2009-06-02 | — | — | US | disclosed |
| US-20060217403-A1 | Substituted 2-aminoacetamides and the use thereof | PURDUE NEUROSCIENCE COMPANY | 2006-09-28 | — | — | US | disclosed |
| US-6281211-B1 | TREATING A DISORDER RESPONSIVE TO THE BLOCKADE OF SODIUM CHANNELS | EURO-CELTIQUE S.A. (LU) | 2001-08-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060217403-A1 | Substituted 2-aminoacetamides and the use thereof | SLC1A2, GAP43, SCN2A | ADORA3 226/4885GRM5 354/4885PRKDC 3004/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.