Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAPGEF4 | Q8WZA2 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.48 |
| ▸ | IKBKB | O14920 | 1/20 | 0.41 |
| ▸ | CHUK | O15111 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | MAOB | P27338 | 2/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.39 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.38 |
| ▸ | MAOA | P21397 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | CNR1 | P21554 | 1/20 | 0.36 |
| ▸ | CNR2 | P34972 | 1/20 | 0.36 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6382158 | 0.85 | ALDH1A1 (0.40) | RAPGEF4ALDH1A1SMN1; SMN2MEN1MAPT | |
| SCHEMBL1044722 | 0.82 | MEN1 (0.47) | RAPGEF4ALDH1A1SMN1; SMN2MEN1MAPT | |
| SCHEMBL23369619 | 0.78 | RAPGEF4 (0.38) | RAPGEF4ALDH1A1SMN1; SMN2MEN1MAPT | |
| SCHEMBL20595546 | 0.78 | RAPGEF4 (0.38) | RAPGEF4ALDH1A1SMN1; SMN2MEN1MAPT | |
| SCHEMBL13312937 | 0.78 | MAOA (0.47) | ALDH1A1IKBKBCHUKSMN1; SMN2NPC1 | |
| SCHEMBL24608797 | 0.77 | ALDH1A1 (0.38) | RAPGEF4ALDH1A1SMN1; SMN2MEN1MAPT | |
| SCHEMBL17180546 | 0.76 | PSMB5 (0.47) | ALDH1A1SMN1; SMN2MEN1KMT2AMAPK1 | |
| SCHEMBL23735474 | 0.76 | ALDH1A1 (0.36) | RAPGEF4ALDH1A1SMN1; SMN2MEN1MAPT | |
| SCHEMBL2843928 | 0.76 | ALDH1A1 (0.40) | RAPGEF4ALDH1A1SMN1; SMN2MEN1MAPT | |
| SCHEMBL2846017 | 0.76 | SENP1 (0.54) | RAPGEF4ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118271332-A | Organic compound and display panel | 武汉华星光电半导体显示技术有限公司 | 2024-07-02 | — | — | CN | disclosed |
| US-7517828-B2 | Chiral broensted acid catalyst for asymmetric synthesis and method of asymmetric synthesis with the catalyst | TOAGOSEI CO., LTD. (JP) | 2009-04-14 | — | — | US | disclosed |
| US-20060276329-A1 | Asymmetric synthesis catalyst based on chiral brsnsted acid and method of asymmetric synthesis with the catalyst | TOAGOSEI CO., LTD. (JP) | 2006-12-07 | — | — | US | disclosed |
| EP-1623971-A1 | ASYMMETRIC-SYNTHESIS CATALYST BASED ON CHIRAL BROENSTED ACID AND METHOD OF ASYMMETRIC SYNTHESIS WITH THE CATALYST | TOAGOSEI CO., LTD. (JP) | 2006-02-08 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060276329-A1 | Asymmetric synthesis catalyst based on chiral brsnsted acid and method of asymmetric synthesis with the catalyst | LSS, COASY, FASN | RAPGEF4 1624/4885ALDH1A1 1508/4885IKBKB 3586/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.