SCHEMBL392901

SCHEMBL392901

CC(=O)Oc1cc(OC(C)=O)cc(C(=O)Cl)c1

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 4/20 0.47
MAPT P10636 3/20 0.47
MEN1 O00255 3/20 0.47
KMT2A Q03164 3/20 0.47
CYP3A4 P08684 2/20 0.47
KDM4E B2RXH2 2/20 0.47
TTR P02766 1/20 0.47
TP53 P04637 1/20 0.47
SMN1; SMN2 Q16637 1/20 0.47
CYP19A1 P11511 1/20 0.43
ELANE P08246 1/20 0.42
CYP4F2 P78329 1/20 0.42
CYP4A11 Q02928 1/20 0.42
BACE1 P56817 1/20 0.42
HSD17B10 Q99714 1/20 0.41
POLB P06746 1/20 0.39
PKM P14618 1/20 0.39
ACHE P22303 2/20 0.39
GAA P10253 1/20 0.39
MAPK1 P28482 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL195019 0.96 LMNA (0.43) LMNAMAPTMEN1KMT2ACYP3A4
SCHEMBL13259257 0.91 LMNA (0.41) LMNAMAPTMEN1KMT2ACYP3A4
SCHEMBL10148964 0.88 LMNA (0.50) LMNAMAPTMEN1KMT2ACYP3A4
SCHEMBL19036064 0.86 LMNA (0.38) LMNAMAPTMEN1KMT2ACYP3A4
SCHEMBL3680093 0.85 LMNA (0.39) LMNAMAPTMEN1KMT2ACYP3A4
SCHEMBL5183332 0.85 PTPN1 (0.39) LMNAMAPTMEN1KMT2ACYP3A4
SCHEMBL2010436 0.83 LMNA (0.59) LMNAMAPTMEN1KMT2ACYP3A4
SCHEMBL16953510 0.82 LMNA (0.50) LMNAMAPTMEN1KMT2ACYP3A4
SCHEMBL414964 0.82 LMNA (0.50) LMNAMAPTMEN1KMT2ACYP3A4
SCHEMBL11699992 0.82 MEN1 (0.32) MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 99 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1753708-A4 NOVEL SIRTUIN ACTIVATING COMPOUNDS AND METHODS FOR MAKING THE SAME UNIV BRIGHAM YOUNG (US) 2007-12-26 EP claimed
EP-1753708-A2 NOVEL SIRTUIN ACTIVATING COMPOUNDS AND METHODS FOR MAKING THE SAME Brigham Young University (US) 2007-02-21 EP claimed
WO-2005069998-A2 NOVEL SIRTUIN ACTIVATING COMPOUNDS AND METHODS FOR MAKING THE SAME BRIGHAM YOUNG UNIVERSITY TECHNOLOGY TRANSFER OFFICE (US) 2005-08-04 WO claimed
CN-118420440-A Preparation method of trans-resveratrol 河北科技大学 2024-08-02 CN disclosed
US-11702509-B2 Monomer, polymer, compensation film, optical film, and display device SAMSUNG ELECTRONICS CO., LTD. (KR) 2023-07-18 US disclosed
US-11702509-B2 Monomer, polymer, compensation film, optical film, and display device SAMSUNG ELECTRONICS CO., LTD. (KR) 2023-07-18 US disclosed
US-20200377659-A1 MONOMER, POLYMER, COMPENSATION FILM, OPTICAL FILM, AND DISPLAY DEVICE SAMSUNG ELECTRONICS CO LTD (KR) 2020-12-03 US disclosed
US-10808080-B2 Monomer, polymer, compensation film, optical film, and display device SAMSUNG ELECTRONICS CO, LTD. (KR) 2020-10-20 US disclosed
US-20200188878-A1 MOLECULARLY IMPRINTED POLYMERS MONASH UNIVERSITY (AU) 2020-06-18 US disclosed
US-20200188878-A1 MOLECULARLY IMPRINTED POLYMERS MONASH UNIVERSITY (AU) 2020-06-18 US disclosed
US-20190031831-A1 MONOMER, POLYMER, COMPENSATION FILM, OPTICAL FILM, AND DISPLAY DEVICE SAMSUNG ELECTRONICS CO., LTD. (KR) 2019-01-31 US disclosed
US-5821039-A PROVIDES BLACK AND WHITE IMAGE USING CONVENTIONAL COLOR NEGATIVE PROCESSING EASTMAN KODAK COMPANY (US) 1998-10-13 US disclosed
US-5661153-A FOR TREATING ALLERGIES, ASTHMA, DERMATITIS, GRAFT REJECTIONS JAPAN ENERGY CORPORATION (JP) 1997-08-26 US disclosed
EP-0700908-A1 1-Arylpyrimidine derivatives and pharmaceutical use thereof JAPAN ENERGY CORPORATION (JP) 1996-03-13 EP disclosed
US-5324804-A Photoresist material based on polystyrenes CIBA-GEIGY CORPORATION (US) 1994-06-28 US disclosed
EP-0250361-B1 Disubstituted piperazines CIBA GEIGY AG (CH) 1993-12-08 EP disclosed
US-4897391-A Tricyclic anti-allergy, antiinflammatory and anti-hyperproliferative compounds SCHERING CORPORATION (US) 1990-01-30 US disclosed
US-4804661-A ANALGESICS CIBA-GEIGY CORPORATION (US) 1989-02-14 US disclosed
EP-0250361-A2 Disubstituted piperazines CIBA-GEIGY AG (CH) 1987-12-23 EP disclosed
US-4036857-A TRANQUILIZERS, ANTIDEPRESSANTS SHARPS ASSOCIATES (US) 1977-07-19 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20190031831-A1 MONOMER, POLYMER, COMPENSATION FILM, OPTICAL FILM, AND DISPLAY DEVICE RAP1A, PYM1, COL1A1 LMNA 1119/4885MAPT 780/4885MEN1 81/4885
US-20200377659-A1 MONOMER, POLYMER, COMPENSATION FILM, OPTICAL FILM, AND DISPLAY DEVICE PYM1, PADI1, COL1A1 LMNA 1639/4885MAPT 740/4885MEN1 106/4885
US-11702509-B2 Monomer, polymer, compensation film, optical film, and display device PYM1, PADI1, COL1A1 LMNA 1639/4885MAPT 740/4885MEN1 106/4885
US-10808080-B2 Monomer, polymer, compensation film, optical film, and display device RAP1A, PYM1, COL1A1 LMNA 1119/4885MAPT 780/4885MEN1 81/4885
US-20200188878-A1 MOLECULARLY IMPRINTED POLYMERS IPMK, MPI, PIM3 LMNA 3479/4885MAPT 3368/4885MEN1 698/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.