SCHEMBL195019

SCHEMBL195019

CC(=O)Oc1cc(C(=O)Cl)cc(C(=O)Cl)c1

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 4/20 0.43
MEN1 O00255 3/20 0.43
KMT2A Q03164 3/20 0.43
MAPT P10636 3/20 0.43
CYP3A4 P08684 2/20 0.43
KDM4E B2RXH2 2/20 0.43
TP53 P04637 2/20 0.43
SMN1; SMN2 Q16637 2/20 0.43
TTR P02766 1/20 0.43
ELANE P08246 1/20 0.42
CYP4F2 P78329 1/20 0.42
CYP4A11 Q02928 1/20 0.42
BACE1 P56817 1/20 0.42
HSD17B10 Q99714 1/20 0.41
CYP19A1 P11511 1/20 0.40
POLB P06746 1/20 0.39
PKM P14618 1/20 0.39
ACHE P22303 2/20 0.39
GAA P10253 1/20 0.39
MAPK1 P28482 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL392901 0.96 LMNA (0.47) LMNAMEN1KMT2AMAPTCYP3A4
SCHEMBL10148964 0.88 LMNA (0.50) LMNAMEN1KMT2AMAPTCYP3A4
SCHEMBL13259257 0.87 LMNA (0.41) LMNAMEN1KMT2AMAPTCYP3A4
SCHEMBL19036064 0.82 LMNA (0.38) LMNAMEN1KMT2AMAPTCYP3A4
SCHEMBL13586886 0.82 LMNA (0.46) LMNAMEN1KMT2AMAPTCYP3A4
SCHEMBL890486 0.82 POLB (0.31) POLBALDH1A1
SCHEMBL2734757 0.81 CYP4F2 (0.43) LMNAMEN1KMT2AMAPTCYP3A4
SCHEMBL3680093 0.81 LMNA (0.39) LMNAMEN1KMT2AMAPTCYP3A4
SCHEMBL5183332 0.81 PTPN1 (0.39) LMNAMEN1KMT2AMAPTCYP3A4
SCHEMBL539733 0.80 LMNA (0.59) LMNAMEN1KMT2AMAPTCYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9290692-B2 Polymer light-emitting material, method for producing the same, and organic electroluminescent device NIPPON STEEL & SUMIKIN CHEMICAL CO., LTD. (JP) 2016-03-22 US disclosed
US-9290692-B2 Polymer light-emitting material, method for producing the same, and organic electroluminescent device NIPPON STEEL & SUMIKIN CHEMICAL CO., LTD. (JP) 2016-03-22 US disclosed
EP-2402413-B1 POLYMER LIGHT-EMITTING MATERIAL, METHOD FOR PRODUCING SAME, AND ORGANIC ELECTROLUMINESCENT ELEMENT NIPPON STEEL & SUMIKIN CHEM CO (JP) 2015-07-22 EP disclosed
EP-2402413-B1 POLYMER LIGHT-EMITTING MATERIAL, METHOD FOR PRODUCING SAME, AND ORGANIC ELECTROLUMINESCENT ELEMENT NIPPON STEEL & SUMIKIN CHEM CO (JP) 2015-07-22 EP disclosed
US-8895691-B2 Acid-labile polymers and monomers for their construction THE RESEARCH FOUNDATION OF STATE UNIVERSITY OF NEW YORK (US) 2014-11-25 US disclosed
US-8895691-B2 Acid-labile polymers and monomers for their construction THE RESEARCH FOUNDATION OF STATE UNIVERSITY OF NEW YORK (US) 2014-11-25 US disclosed
US-8895691-B2 Acid-labile polymers and monomers for their construction THE RESEARCH FOUNDATION OF STATE UNIVERSITY OF NEW YORK (US) 2014-11-25 US disclosed
US-8404795-B2 Photolytic acid-generating polymers and monomers for their construction THE RESEARCH FOUNDATION FOR THE STATE UNIVERSITY OF NEW YORK (US) 2013-03-26 US disclosed
US-8404795-B2 Photolytic acid-generating polymers and monomers for their construction THE RESEARCH FOUNDATION FOR THE STATE UNIVERSITY OF NEW YORK (US) 2013-03-26 US disclosed
EP-2402413-A1 POLYMER LIGHT-EMITTING MATERIAL, METHOD FOR PRODUCING SAME, AND ORGANIC ELECTROLUMINESCENT ELEMENT Nippon Steel Chemical Co., Ltd. (JP) 2012-01-04 EP disclosed
US-20110152496-A1 ACID-LABILE POLYMERS AND MONOMERS FOR THEIR CONSTRUCTION THE RESEARCH FOUNDATION OF STATE UNIVERSITY OF NEW YORK (US) 2011-06-23 US disclosed
US-20110152496-A1 ACID-LABILE POLYMERS AND MONOMERS FOR THEIR CONSTRUCTION THE RESEARCH FOUNDATION OF STATE UNIVERSITY OF NEW YORK (US) 2011-06-23 US disclosed
US-20110130538-A1 PHOTOLYTIC ACID-GENERATING POLYMERS AND MONOMERS FOR THEIR CONSTRUCTION THE RESEARCH FOUNDATION OF THE STATE UNIVERSITY OF NEW YORK (US) 2011-06-02 US disclosed
US-20110130538-A1 PHOTOLYTIC ACID-GENERATING POLYMERS AND MONOMERS FOR THEIR CONSTRUCTION THE RESEARCH FOUNDATION OF THE STATE UNIVERSITY OF NEW YORK (US) 2011-06-02 US disclosed
US-20110009584-A1 Romp-Polymerizable Electron Transport Materials Based On A Bis-Oxadiazole Moiety GEORGIA TECH RESEARCH CORPORATION (US) 2011-01-13 US disclosed
US-20110009584-A1 Romp-Polymerizable Electron Transport Materials Based On A Bis-Oxadiazole Moiety GEORGIA TECH RESEARCH CORPORATION (US) 2011-01-13 US disclosed
EP-2234991-A1 ROMP-POLYMERIZABLE ELECTRON TRANSPORT MATERIALS BASED ON A BIS-OXADIAZOLE MOIETY Georgia Tech Research Corporation (US) 2010-10-06 EP disclosed
WO-2009080797-A1 ROMP-POLYMERIZABLE ELECTRON TRANSPORT MATERIALS BASED ON A BIS-OXADIAZOLE MOIETY GEORGIA TECH RESEARCH CORPORATION (US) 2009-07-02 WO disclosed
WO-2009080797-A1 ROMP-POLYMERIZABLE ELECTRON TRANSPORT MATERIALS BASED ON A BIS-OXADIAZOLE MOIETY GEORGIA TECH RESEARCH CORPORATION (US) 2009-07-02 WO disclosed
US-6743889-B1 3,5-BIS(4-FLUOROBENZOYL)PHENOL WITH 4-FLUORO-4'-HYDROXY-BENZOPHENONE THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE AIR FORCE 2004-06-01 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110009584-A1 Romp-Polymerizable Electron Transport Materials Based On A Bis-Oxadiazole Moiety SLCO1B3, SLCO4C1, SLCO2B1 LMNA 3705/4885MEN1 2411/4885KMT2A 4680/4885
US-20110130538-A1 PHOTOLYTIC ACID-GENERATING POLYMERS AND MONOMERS FOR THEIR CONSTRUCTION PPOX, ALAD, PGAM1 LMNA 4128/4885MEN1 4219/4885KMT2A 2421/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.