Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4004713 | 0.84 | MTNR1A (0.43) | MEN1GAAKMT2ANPSR1TSHR | |
| SCHEMBL4006804 | 0.73 | MEN1 (0.46) | MEN1GAAKMT2ANPSR1TSHR | |
| SCHEMBL4375638 | 0.72 | KCNA5 (0.47) | MEN1KMT2ANPSR1TSHR | |
| SCHEMBL4370911 | 0.71 | USP2 (0.48) | MEN1GAAKMT2ANPSR1TSHR | |
| SCHEMBL3934300 | 0.71 | ALDH1A1 (0.54) | MEN1KMT2ANPSR1TSHR | |
| SCHEMBL4009792 | 0.71 | TSHR (0.45) | GAANPSR1TSHR | |
| SCHEMBL4164264 | 0.67 | KCNA5 (0.56) | MEN1KMT2ANPSR1TSHR | |
| SCHEMBL3937415 | 0.66 | TP53 (0.51) | MEN1KMT2ANPSR1TSHR | |
| SCHEMBL3931555 | 0.66 | ALDH1A1 (0.69) | MEN1KMT2ANPSR1TSHR | |
| SCHEMBL4363829 | 0.66 | ALDH1A1 (0.54) | MEN1KMT2ANPSR1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090291983-A1 | 3-Oxoisoindoline-1-Carboxamide Derivatives as Analgesic Agents | ASTRAZENECA AB (SE) | 2009-11-26 | — | — | US | claimed |
| EP-2044019-A1 | 3-OXOISOINDOLINE-1-CARBOXAMIDE DERIVATIVES AS ANALGESIC AGENTS | Astra Zeneca AB (SE) | 2009-04-08 | — | — | EP | claimed |
| WO-2008008020-A1 | 3-OXOISOINDOLINE-1-CARBOXAMIDE DERIVATIVES AS ANALGESIC AGENTS | ASTRAZENECA AB (SE) | 2008-01-17 | — | — | WO | claimed |
| US-20090291983-A1 | 3-Oxoisoindoline-1-Carboxamide Derivatives as Analgesic Agents | ASTRAZENECA AB (SE) | 2009-11-26 | — | — | US | disclosed |
| EP-2044019-A1 | 3-OXOISOINDOLINE-1-CARBOXAMIDE DERIVATIVES AS ANALGESIC AGENTS | Astra Zeneca AB (SE) | 2009-04-08 | — | — | EP | disclosed |
| WO-2008008020-A1 | 3-OXOISOINDOLINE-1-CARBOXAMIDE DERIVATIVES AS ANALGESIC AGENTS | ASTRAZENECA AB (SE) | 2008-01-17 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090291983-A1 | 3-Oxoisoindoline-1-Carboxamide Derivatives as Analgesic Agents | OPRD1, OPRK1, OPRM1 | MEN1 2067/4885GAA 3678/4885KMT2A 1653/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.