Known targets — ChEMBL curated mechanism
ABCC9ABL1ACEACHEACVR1ADORA1ADORA2AADORA2BADORA3ADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3AGTR1ALOX5ATP4AATP4BBCRBTKCACNA1ACACNA1BCACNA1CCACNA1DCACNA1ECACNA1FCACNA1GCACNA1HCACNA1ICACNA1SCACNA2D1CACNA2D2CACNA2D3CACNA2D4CACNB1CACNB2CACNB3CACNB4CACNG1CACNG2CACNG3CACNG4CACNG5CACNG6CACNG7CACNG8CALCRLCFBCHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNB1CHRNDCHRNECHRNGCRBNCUL4ACXCR1CXCR2DDB1DDCDHFRDPP4DRD2DRD3DRD4EGFRERBB2ERBB4ESR1ESR2FDPSFKBP1AFLT1FLT3FLT4GARTGHSRGRIA1GRIA2GRIA3GRIA4GRIK1GRIK2GRIK3GRIK4GRIK5GRIN2AGSK3AGSK3BHDAC1HDAC10HDAC11HDAC2HDAC3HDAC4HDAC5HDAC6HDAC7HDAC8HDAC9HRH1HTR1AHTR1BHTR1DHTR1EHTR1FHTR2AHTR2BHTR2CHTR3AHTR3BHTR3CHTR3DHTR3EHTR4HTR5AHTR6HTR7IDH1IDH2IMPA1ITGA2BITGB3JAK1JAK2JAK3KCNJ11KCNK3KCNK9KDRKITMEN1METMMP1MMP13MMP7MMP8NANOD2NS5bODC1OPG057OPRD1OPRK1OPRM1PPARP1PARP2PDE3APDE3BPDE4APDE4BPDE4CPDE4DPDGFRBPIK3CAPIK3CBPIK3CDPIK3CGPIK3R1PIK3R2PIK3R3PIK3R5PKLRPPARDPPATPTGS1PTGS2RBX1ROCK1ROCK2RRM1RRM2RRM2BSCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASCNN1ASCNN1BSCNN1GSIGMAR1SLC10A2SLC5A2SLC6A2SLC6A3SLC6A4SLC9A3SYKTACR1THRATHRBTOP1TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8TYK2TYMSVDRampCblablaT-3blaT-4blaT-5blaT-6blaUOE-1dacAdacBdacCfolAfolPftsIgyrAgyrBileSmecAmrcAmrcBmrdAparCparEpbp2pbp4pbpApbpFrplArplBrplCrplDrplErplFrplIrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmE2rpmFrpmGrpmG1rpmG2rpmG3rpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUthyAykgMykgO
The experimentally established mechanism targets of Water. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Water SCHEMBL9845420 | 1.00 | HSP90AA1 (0.33) | HSP90AA1 | |
| Water SCHEMBL10918567 | 1.00 | — | — | |
| SCHEMBL27007968 | 0.93 | HSP90AA1 (0.36) | HSP90AA1 | |
| SCHEMBL8512657 | 0.93 | HSP90AA1 (0.36) | HSP90AA1 | |
| SCHEMBL25412605 | 0.86 | — | — | |
| Hydrochloric Acid SCHEMBL8881787 | 0.86 | — | — | |
| SCHEMBL11226761 | 0.86 | — | — | |
| SCHEMBL11643137 | 0.86 | — | — | |
| SCHEMBL11215215 | 0.86 | — | — | |
| SCHEMBL904361 | 0.86 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 46 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-100351287-C | Products, especially moulding materials of polymers containing triazine segments, method for the production thereof and uses of the same | AMI AGROLINZ MELAMINE INT GMBH (AT) | 2007-11-28 | — | — | CN | claimed |
| EP-1603969-B1 | PRE-IMPREGNATING AGENTS FOR HIGH-RESISTANT AND ELASTIC COMPOSITE FIBRES | AMI AGROLINZ MELAMINE INT GMBH (AT) | 2007-10-03 | — | — | EP | claimed |
| EP-1448671-B1 | PRODUCTS, ESPECIALLY MOULDING MATERIALS OF POLYMERS CONTAINING TRIAZINE SEGMENTS, METHOD FOR THE PRODUCTION THEREOF AND USES OF THE SAME | AMI AGROLINZ MELAMINE INT GMBH (AT) | 2007-09-12 | — | — | EP | claimed |
| US-20070048522-A1 | Prepregs for fiber composites having high strength and resilience | AMI - AGROLINZ MELAMINE INTERNATIONAL GMBH (AT) | 2007-03-01 | — | — | US | claimed |
| CN-1298758-C | Compositions for producing aminoplast products and method for producing products from these compositions | AMI AGROLINZ MELAMINE INT GMBH (AT) | 2007-02-07 | — | — | CN | claimed |
| CN-1662571-A | Compositions for preparing amino resin products and process for preparing products with these compositions | AMI AGROLINZ MELAMINE INT GMBH (AT) | 2005-08-31 | — | — | CN | claimed |
| CN-1615330-A | Products, especially moulding materials of polymers containing triazine segments, method for the production thereof and uses of the same | AMI AGROLINZ MELAMINE INT GMBH (AT) | 2005-05-11 | — | — | CN | claimed |
| US-20050038226-A1 | Products, especially moulding materials of polymers containing triazine segments, method for the production thereof and uses of the same | BOREALIS AG (AT) | 2005-02-17 | — | — | US | claimed |
| EP-0460101-A4 | IMMOBILIZED CYTOKINES | — | 1992-04-15 | — | — | EP | claimed |
| EP-0460101-A1 | IMMOBILIZED CYTOKINES | IMMUNOTHERAPEUTICS, INC. (US) | 1991-12-11 | — | — | EP | claimed |
| WO-1990009798-A1 | IMMOBILIZED CYTOKINES | IMMUNOTHERAPEUTICS, INC. (US) | 1990-09-07 | — | — | WO | claimed |
| EP-0160218-B1 | PROCESS FOR PREPARING C8 -C24 ALKYLBENZENE SULFONYLAZIDES | MERCK & CO. INC. (US) | 1987-10-21 | — | — | EP | claimed |
| EP-0160218-A1 | Process for preparing C8 -C24 alkylbenzene sulfonylazides | MERCK & CO. INC. (US) | 1985-11-06 | — | — | EP | claimed |
| CN-108473505-B | Polyfluoreno [4,5-cde ] oxepine conjugates and their use in analyte detection methods | 阿特生物探索公司 | 2019-11-05 | — | — | CN | disclosed |
| CN-108473505-A | Polyfluoreno [4,5-cde ] oxepine conjugates and their use in analyte detection methods | 阿特生物探索公司 | 2018-08-31 | — | — | CN | disclosed |
| WO-2016160168-A1 | ALIPHATIC-AROMATIC HETEROCYCLIC COMPOUNDS AND USES THEREOF IN METAL EXTRACTANT COMPOSITIONS | CYTEC INDUSTRIES INC. (US) | 2016-10-06 | — | — | WO | disclosed |
| EP-0460101-A4 | IMMOBILIZED CYTOKINES | — | 1992-04-15 | — | — | EP | disclosed |
| EP-0460101-A1 | IMMOBILIZED CYTOKINES | IMMUNOTHERAPEUTICS, INC. (US) | 1991-12-11 | — | — | EP | disclosed |
| EP-0160218-B1 | PROCESS FOR PREPARING C8 -C24 ALKYLBENZENE SULFONYLAZIDES | MERCK & CO. INC. (US) | 1987-10-21 | — | — | EP | disclosed |
| EP-0160218-A1 | Process for preparing C8 -C24 alkylbenzene sulfonylazides | MERCK & CO. INC. (US) | 1985-11-06 | — | — | EP | disclosed |