Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.41 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.40 |
| ▸ | NISCH | Q9Y2I1 | 1/20 | 0.40 |
| ▸ | MAOB | P27338 | 2/20 | 0.39 |
| ▸ | MAOA | P21397 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | MGLL | Q99685 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 4/20 | 0.36 |
| ▸ | NPC1 | O15118 | 3/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28516562 | 0.86 | ALDH1A1 (0.41) | ALDH1A1MAPK1SMN1; SMN2MAPTHPGD | |
| SCHEMBL28527734 | 0.81 | TRPA1 (0.52) | ALDH1A1CYP2A6MAOBMAOASMN1; SMN2 | |
| SCHEMBL5101098 | 0.78 | RELA (0.48) | ALDH1A1MAPK1SMN1; SMN2MAPTRAB9A | |
| SCHEMBL6916286 | 0.77 | RAB9A (0.59) | ALDH1A1MAPK1SMN1; SMN2MAPTHPGD | |
| SCHEMBL6916282 | 0.77 | RAB9A (0.59) | ALDH1A1MAPK1SMN1; SMN2MAPTHPGD | |
| SCHEMBL11379736 | 0.77 | ALDH1A1 (0.58) | ALDH1A1MAPK1FFAR1CYP2A6MAOB | |
| SCHEMBL418238 | 0.77 | ALDH1A1 (0.57) | ALDH1A1MAPK1FFAR1MAOBMAOA | |
| SCHEMBL22610209 | 0.77 | ALDH1A1 (0.57) | ALDH1A1MAPK1FFAR1NISCHMAOB | |
| SCHEMBL418239 | 0.77 | ALDH1A1 (0.57) | ALDH1A1MAPK1FFAR1MAOBMAOA | |
| SCHEMBL6553087 | 0.73 | ALDH1A1 (0.42) | ALDH1A1CYP2A6MAOBSMN1; SMN2HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118076360-A | Compositions and methods for targeted RNA delivery | 维乎医疗有限公司 | 2024-05-24 | — | — | CN | disclosed |
| CN-112390697-B | Synthesis method of N-arylselenium/thioethyl sulfoxide imine | 成都理工大学 | 2023-03-10 | — | — | CN | disclosed |
| CN-115484932-A | Compositions and methods for targeted RNA delivery | 维乎医疗有限公司 | 2022-12-16 | — | — | CN | disclosed |
| CN-112390697-A | Synthesis method of N-arylselenium/thioethyl sulfoxide imine | 成都理工大学 | 2021-02-23 | — | — | CN | disclosed |
| EP-2043644-A1 | NF- B INHIBITOR | Otsuka Pharmaceutical Co., Ltd. (JP) | 2009-04-08 | — | — | EP | disclosed |
| WO-2007119600-A9 | CARBAZOLE COMPOUND | OTSUKA PHARMA CO LTD (JP) | 2008-05-02 | — | — | WO | disclosed |
| WO-2008010601-A1 | NF- ϰB INHIBITOR | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2008-01-24 | — | — | WO | disclosed |
| WO-2007119600-A1 | CARBAZOLE COMPOUND | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2007-10-25 | — | — | WO | disclosed |