Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 10/20 | 0.58 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.46 |
| ▸ | TNF | P01375 | 1/20 | 0.43 |
| ▸ | IGF1R | P08069 | 7/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4871345 | 0.81 | GRM4 (0.44) | FAAHGRM4TNFIGF1RNPSR1 | |
| SCHEMBL5793884 | 0.79 | GRM4 (0.39) | FAAHGRM4TNFNPSR1 | |
| SCHEMBL3932151 | 0.75 | FAAH (0.83) | FAAHGRM4IGF1R | |
| SCHEMBL4012253 | 0.74 | FAAH (0.68) | FAAHGRM4TNF | |
| SCHEMBL1922670 | 0.74 | AXL (0.39) | FAAH | |
| SCHEMBL4012669 | 0.73 | FAAH (0.79) | FAAHTNFIGF1R | |
| SCHEMBL4012855 | 0.73 | FAAH (0.79) | FAAHGRM4TNF | |
| SCHEMBL3936220 | 0.73 | FAAH (1.00) | FAAH | |
| SCHEMBL3933752 | 0.73 | FAAH (0.89) | FAAH | |
| SCHEMBL4022295 | 0.73 | FAAH (0.38) | FAAHGRM4TNF |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009011904-A1 | COMPOUNDS USEFUL AS FAAH MODULATORS AND USES THEREOF | RENOVIS, INC. (US) | 2009-01-22 | — | — | WO | disclosed |
| WO-2009011904-A1 | COMPOUNDS USEFUL AS FAAH MODULATORS AND USES THEREOF | RENOVIS, INC. (US) | 2009-01-22 | — | — | WO | disclosed |