Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.36 |
| ▸ | BBOX1 | O75936 | 1/20 | 0.35 |
| ▸ | ASPH | Q12797 | 1/20 | 0.35 |
| ▸ | KDM8 | Q8N371 | 1/20 | 0.35 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.35 |
| ▸ | HIF1AN | Q9NWT6 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL390378 | 0.98 | LMNA (0.39) | LMNAL3MBTL1ALDH1A1KMT2AEPHX1 | |
| SCHEMBL204609 | 0.80 | LMNA (0.54) | LMNAALDH1A1EPHX1BBOX1ASPH | |
| SCHEMBL392016 | 0.79 | ALDH1A1 (0.38) | L3MBTL1ALDH1A1KMT2AEPHX1BBOX1 | |
| SCHEMBL390786 | 0.78 | ADRB2 (0.37) | L3MBTL1ALDH1A1KMT2AHPGDBBOX1 | |
| SCHEMBL6137896 | 0.74 | RAB9A (0.56) | KMT2AEPHX1HPGDNPC1RAB9A | |
| SCHEMBL392299 | 0.74 | ATM (0.38) | L3MBTL1ALDH1A1KMT2AHPGDEGLN1 | |
| SCHEMBL393503 | 0.73 | ALDH1A1 (0.37) | LMNAL3MBTL1ALDH1A1KMT2AHPGD | |
| SCHEMBL17928598 | 0.73 | L3MBTL1 (0.43) | LMNAL3MBTL1ALDH1A1KMT2AEPHX1 | |
| SCHEMBL13546279 | 0.72 | RAB9A (0.53) | ALDH1A1KMT2AEPHX1HPGDNPC1 | |
| SCHEMBL13618451 | 0.71 | L3MBTL1 (0.44) | LMNAL3MBTL1ALDH1A1KMT2AEPHX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8101590-B2 | 9-aminocarbonylsubstituted derivatives of glycylcyclines | WYETH LLC (US) | 2012-01-24 | — | — | US | disclosed |
| US-20070049564-A1 | 9-Aminocarbonylsubstituted derivatives of glycylcyclines | WYETH (US) | 2007-03-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070049564-A1 | 9-Aminocarbonylsubstituted derivatives of glycylcyclines | Q6ZSR9, GMPS, RPS10 | LMNA 2954/4885L3MBTL1 3336/4885ALDH1A1 1826/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.