SCHEMBL3933299

SCHEMBL3933299

CC(C)(C)[Si](OCCCCN)(c1ccccc1)c1ccccc1

nearest known ligand 0.43

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 2/20 0.37
SMYD2 Q9NRG4 2/20 0.37
CYP3A4 P08684 1/20 0.37
HTT P42858 1/20 0.37
MAOA P21397 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15645028 0.98 SMN1; SMN2 (0.37) SMN1; SMN2SMYD2CYP3A4HTTMAOA
SCHEMBL31400145 0.98 SMN1; SMN2 (0.37) SMN1; SMN2SMYD2CYP3A4HTTMAOA
SCHEMBL3939837 0.98 SMN1; SMN2 (0.37) SMN1; SMN2SMYD2CYP3A4HTTMAOA
SCHEMBL2818126 0.95 SMN1; SMN2 (0.38) SMN1; SMN2SMYD2CYP3A4HTT
SCHEMBL12987807 0.90 SMYD2 (0.33) SMN1; SMN2SMYD2CYP3A4HTT
SCHEMBL12988245 0.90 SMYD2 (0.33) SMN1; SMN2SMYD2CYP3A4HTT
SCHEMBL15644367 0.90 SMYD2 (0.33) SMN1; SMN2SMYD2CYP3A4HTT
Butylamine SCHEMBL20954570 0.89 SMN1; SMN2 (0.38) SMN1; SMN2SMYD2CYP3A4HTT
SCHEMBL453430 0.88 SMN1; SMN2 (0.44) SMN1; SMN2SMYD2CYP3A4HTT
SCHEMBL4863255 0.87 IDO1 (0.42) SMN1; SMN2SMYD2CYP3A4HTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 40 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4638417-A1 SULFUR-CONTAINING IONIZABLE LIPIDS FOR THE DELIVERY OF NUCLEIC ACIDS AND OTHER THERAPEUTIC AGENTS Nanovation Therapeutics Inc. (CA) 2025-10-29 EP disclosed
US-20250304547-A1 Sulfur-Containing Lipids NANOVATION THERAPEUTICS INC. (CA) 2025-10-02 US disclosed
EP-4594300-A1 SULFUR-CONTAINING IONIZABLE LIPIDS FOR THE DELIVERY OF THERAPEUTIC AGENTS Nanovation Therapeutics Inc. (CA) 2025-08-06 EP disclosed
WO-2025035202-A1 IONIZABLE LIPIDS COMPRISING MACROCYCLIC RINGS FOR THE DELIVERY OF THERAPEUTIC AGENTS NANOVATION THERAPEUTICS INC. (CA) 2025-02-20 WO disclosed
US-20240398977-A1 SULFUR-CONTAINING IONIZABLE LIPIDS FOR THE DELIVERY OF NUCLEIC ACIDS AND OTHER THERAPEUTIC AGENTS NANOVATION THERAPEUTICS INC. (CA) 2024-12-05 US disclosed
US-12121591-B2 Sulfur-containing ionizable lipids for the delivery of nucleic acids and other therapeutic agents NANOVATION THERAPEUTICS INC. (CA) 2024-10-22 US disclosed
US-20240294462-A1 Method for the Synthesis of Ionizable Lipids Using a Doubly Alkylated Intermediate NANOVATION THERAPEUTICS INC. (CA) 2024-09-05 US disclosed
US-20240261430-A1 SULFUR-CONTAINING IONIZABLE LIPIDS FOR THE DELIVERY OF NUCLEIC ACIDS AND OTHER THERAPEUTIC AGENTS NANOVATION THERAPEUTICS INC. (CA) 2024-08-08 US disclosed
WO-2024130421-A1 SULFUR-CONTAINING IONIZABLE LIPIDS FOR THE DELIVERY OF NUCLEIC ACIDS AND OTHER THERAPEUTIC AGENTS NANOVATION THERAPEUTICS INC. (CA) 2024-06-27 WO disclosed
WO-2024065041-A1 SULFUR-CONTAINING IONIZABLE LIPIDS FOR THE DELIVERY OF THERAPEUTIC AGENTS NANOVATION THERAPEUTICS INC. (CA) 2024-04-04 WO disclosed
US-20030092643-A1 Aminoalkyl glucosaminide phosphate compounds and their use as adjuvants and immunoeffectors CORIXA CORPORATION 2003-05-15 US disclosed
CN-1409720-A Aminoalkyl glucosaminide phosphate compounds and their use as adjuvants and immunoeffectors CORIXA CORP (US) 2003-04-09 CN disclosed
EP-1230250-A2 AMINOALKYL GLUCOSAMINIDE PHOSPHATE COMPOUNDS AND THEIR USE AS ADJUVANTS AND IMMUNOEFFECTORS CORIXA CORPORATION (US) 2002-08-14 EP disclosed
US-20020048588-A1 Aminoalkyl glucosaminide phosphate compounds and their use as adjuvants and immunoeffectors CORIXA CORPORATION 2002-04-25 US disclosed
US-6355257-B1 Aminoalkyl glucosamine phosphate compounds and their use as adjuvants and immunoeffectors CORIXA CORPORATION 2002-03-12 US disclosed
US-6303347-B1 VACCINES CORIXA CORPORATION 2001-10-16 US disclosed
WO-2001034617-A2 AMINOALKYL GLUCOSAMINIDE PHOSPHATE COMPOUNDS AND THEIR USE AS ADJUVANTS AND IMMUNOEFFECTORS CORIXA CORPORATION (US) 2001-05-17 WO disclosed
US-6113918-A IMMUNOLOGY RIBI IMMUNOCHEM RESEARCH, INC. (US) 2000-09-05 US disclosed
EP-0983286-A1 AMINOALKYL GLUCOSAMINE PHOSPHATE COMPOUNDS AND THEIR USE AS ADJUVANTS AND IMMUNOEFFECTORS CORIXA CORPORATION (US) 2000-03-08 EP disclosed
WO-1998050399-A1 AMINOALKYL GLUCOSAMINE PHOSPHATE COMPOUNDS AND THEIR USE AS ADJUVANTS AND IMMUNOEFFECTORS CORIXA CORPORATION (US) 1998-11-12 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12121591-B2 Sulfur-containing ionizable lipids for the delivery of nucleic acids and other therapeutic agents SLC43A1, NSUN3, NSUN2 SMN1; SMN2 919/4885SMYD2 413/4885CYP3A4 4678/4885
US-20020048588-A1 Aminoalkyl glucosaminide phosphate compounds and their use as adjuvants and immunoeffectors DNPEP, CD68, MGAT3 SMN1; SMN2 4820/4885SMYD2 2362/4885CYP3A4 3571/4885
US-20240261430-A1 SULFUR-CONTAINING IONIZABLE LIPIDS FOR THE DELIVERY OF NUCLEIC ACIDS AND OTHER THERAPEUTIC AGENTS SLC43A1, NSUN3, NSUN2 SMN1; SMN2 919/4885SMYD2 413/4885CYP3A4 4678/4885
US-20030092643-A1 Aminoalkyl glucosaminide phosphate compounds and their use as adjuvants and immunoeffectors DNPEP, CD68, MGAT3 SMN1; SMN2 4817/4885SMYD2 2464/4885CYP3A4 3535/4885
US-20240294462-A1 Method for the Synthesis of Ionizable Lipids Using a Doubly Alkylated Intermediate SGMS1, SGMS2, LIPC SMN1; SMN2 4587/4885SMYD2 1015/4885CYP3A4 934/4885
US-20240398977-A1 SULFUR-CONTAINING IONIZABLE LIPIDS FOR THE DELIVERY OF NUCLEIC ACIDS AND OTHER THERAPEUTIC AGENTS SLC43A1, NSUN3, NSUN2 SMN1; SMN2 919/4885SMYD2 413/4885CYP3A4 4678/4885
US-20250304547-A1 Sulfur-Containing Lipids FABP1, SLC10A1, MPST SMN1; SMN2 1685/4885SMYD2 475/4885CYP3A4 4255/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.