Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IKBKB | O14920 | 1/20 | 0.46 |
| ▸ | PIK3CD | O00329 | 2/20 | 0.44 |
| ▸ | PIK3CA | P42336 | 2/20 | 0.44 |
| ▸ | PIK3CB | P42338 | 2/20 | 0.44 |
| ▸ | PIK3CG | P48736 | 2/20 | 0.44 |
| ▸ | CA1 | P00915 | 1/20 | 0.42 |
| ▸ | CA2 | P00918 | 1/20 | 0.42 |
| ▸ | CA9 | Q16790 | 1/20 | 0.42 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | PRKCZ | Q05513 | 2/20 | 0.40 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | PORCN | Q9H237 | 1/20 | 0.40 |
| ▸ | DYRK3 | O43781 | 1/20 | 0.40 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.40 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1401395 | 0.81 | CA1 (0.44) | IKBKBPIK3CDPIK3CAPIK3CBPIK3CG | |
| SCHEMBL1395608 | 0.78 | CA2 (0.66) | CA1CA2CA9ALDH1A1MAPT | |
| SCHEMBL127857 | 0.77 | CYP11B2 (0.58) | IKBKBMAPTCYP3A4NPC1RAB9A | |
| SCHEMBL7287307 | 0.75 | CA1 (0.45) | IKBKBCA1CA2CA9MRGPRX4 | |
| SCHEMBL20364928 | 0.75 | L3MBTL1 (0.56) | CA1CA2CA9ALDH1A1KDM4E | |
| SCHEMBL31499216 | 0.74 | PTGS2 (0.54) | CA1CA2CA9ALDH1A1KDM4E | |
| SCHEMBL12567839 | 0.74 | PIK3CD (0.45) | PIK3CDPIK3CAPIK3CBPIK3CGPRKCZ | |
| SCHEMBL9826855 | 0.73 | CA12 (0.49) | IKBKBCA9MRGPRX4ALDH1A1MAPT | |
| SCHEMBL1395599 | 0.73 | CYP2A6 (0.52) | CA1CA2CA9ALDH1A1MAPT | |
| SCHEMBL30497290 | 0.72 | IKBKB (0.48) | IKBKBMRGPRX4ALDH1A1MAPTPRKCZ |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2043638-A2 | USE OF TRIFLUOROMETHYL SUBSTITUTED BENZAMIDES IN THE TREATMENT OF NEUROLOGICAL DISORDERS | Novartis AG (CH) | 2009-04-08 | — | — | EP | disclosed |
| WO-2008008821-A2 | USE OF TRIFLUOROMETHYL SUBSTITUTED BENZAMIDES IN THE TREATMENT OF NEUROLOGICAL DISORDERS | NOVARTIS AG (CH) | 2008-01-17 | — | — | WO | disclosed |