Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AURKA | O14965 | 4/20 | 0.50 |
| ▸ | NUDT1 | P36639 | 1/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.49 |
| ▸ | NOS1 | P29475 | 1/20 | 0.49 |
| ▸ | NOS2 | P35228 | 1/20 | 0.49 |
| ▸ | METAP1 | P53582 | 2/20 | 0.45 |
| ▸ | METAP2 | P50579 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | DRD4 | P21917 | 1/20 | 0.44 |
| ▸ | PDE5A | O76074 | 5/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | WNT1 | P04628 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | ATM | Q13315 | 1/20 | 0.43 |
| ▸ | PDE4A | P27815 | 1/20 | 0.42 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.42 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL9396770 | 0.98 | AURKA (0.49) | AURKANUDT1CYP2C9NOS1NOS2 | |
| SCHEMBL2314765 | 0.81 | DDAH1 (0.55) | AURKANUDT1CYP2C9NOS1NOS2 | |
| SCHEMBL7002580 | 0.80 | NUDT1 (0.58) | AURKANUDT1CYP2C9NOS1NOS2 | |
| SCHEMBL21101319 | 0.79 | CXCR4 (0.48) | AURKANUDT1CYP2C9NOS1NOS2 | |
| SCHEMBL3960231 | 0.78 | CYP2C9 (0.57) | AURKANUDT1CYP2C9NOS1NOS2 | |
| SCHEMBL4347800 | 0.77 | NUDT1 (0.55) | AURKANUDT1CYP2C9NOS1NOS2 | |
| SCHEMBL6216010 | 0.77 | NUDT1 (0.55) | AURKANUDT1CYP2C9NOS1NOS2 | |
| SCHEMBL31587712 | 0.77 | NUDT1 (0.55) | AURKANUDT1CYP2C9NOS1NOS2 | |
| SCHEMBL3967813 | 0.77 | NUDT1 (0.55) | AURKANUDT1CYP2C9NOS1NOS2 | |
| SCHEMBL4773954 | 0.77 | NUDT1 (0.59) | AURKANUDT1CYP2C9NOS1NOS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009007995-A1 | PROCESS FOR PREPARING ZOLPIDEM AND ITS INTERMEDIATE | SUVEN LIFE SCIENCES LIMITED (IN) | 2009-01-15 | — | — | WO | disclosed |
| EP-0670838-A1 | SUBSTITUTED-PHENYL(N,N'-CYCLOALKYL/ALKYL CARBOXAMIDE)-1H/3H-IMIDAZO 4,5-b]PYRIDINE COMPOUNDS AS PAF ANTAGONISTS | G.D. SEARLE & CO. (US) | 1995-09-13 | — | — | EP | disclosed |
| WO-1994029307-A1 | PYRROLO[3,2-B]PYRIDINYLALKYL BENZAMIDE DERIVATIVES | G.D. SEARLE & CO. (US) | 1994-12-22 | — | — | WO | disclosed |
| US-5359073-A | Substituted-phenyl (N,N'-cycloalkyl/alkyl carboxamide)-1H/3H-imidazo[4,5-b]pyridine compounds as PAF antagonists | G. D. SEARLE & CO. (US) | 1994-10-25 | — | — | US | disclosed |
| WO-1994012500-A1 | SUBSTITUTED-PHENYL(N,N'-CYCLOALKYL/ALKYL CARBOXAMIDE)-1H/3H-IMIDAZO[4,5-b]PYRIDINE COMPOUNDS AS PAF ANTAGONISTS | G.D. SEARLE & CO. (US) | 1994-06-09 | — | — | WO | disclosed |