Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DGAT1 | O75907 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2426288 | 0.91 | NPC1 (0.32) | DGAT1 | |
| SCHEMBL3935157 | 0.87 | DGAT1 (0.33) | DGAT1 | |
| SCHEMBL3925961 | 0.85 | MEN1 (0.30) | DGAT1 | |
| SCHEMBL2425028 | 0.85 | KDM4E (0.33) | DGAT1 | |
| SCHEMBL3935160 | 0.83 | — | — | |
| SCHEMBL2423589 | 0.83 | ALDH1A1 (0.34) | DGAT1 | |
| SCHEMBL3926529 | 0.83 | IDO1 (0.36) | DGAT1 | |
| SCHEMBL2424803 | 0.83 | — | — | |
| SCHEMBL2426759 | 0.80 | — | — | |
| SCHEMBL2425221 | 0.79 | F11 (0.31) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009009411-A1 | SUBSTITUTED HETEROCYCLIC ETHERS AND THEIR USE IN CNS DISORDERS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2009-01-15 | — | — | WO | disclosed |