⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1986740 | 0.74 | TSHR (0.35) | — | |
| SCHEMBL30391714 | 0.74 | TSHR (0.35) | — | |
| SCHEMBL10706514 | 0.65 | TSHR (0.50) | — | |
| SCHEMBL7602941 | 0.65 | TSHR (0.50) | — | |
| SCHEMBL1041344 | 0.63 | ACHE (0.38) | — | |
| SCHEMBL6032835 | 0.63 | — | — | |
| SCHEMBL258502 | 0.63 | TSHR (0.47) | — | |
| SCHEMBL31536312 | 0.63 | ALDH1A1 (0.38) | — | |
| Hydrochloric Acid SCHEMBL15845273 | 0.62 | TSHR (0.45) | — | |
| Hydrochloric Acid SCHEMBL15845267 | 0.62 | TSHR (0.45) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1133357-B1 | POLYMER-SUPPORTED PHOSPHORUS LIGANDS FOR CATALYSIS | DU PONT (US) | 2009-04-15 | — | — | EP | disclosed |
| US-7238841-B2 | Polymer-supported phosphorus ligands for catalysts | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2007-07-03 | — | — | US | disclosed |
| US-7098261-B2 | Polymer-supported phosphorus ligands for catalysis | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2006-08-29 | — | — | US | disclosed |
| EP-1604738-A2 | Process for the preparation of coumarin | E.I. du Pont de Nemours and Company (US) | 2005-12-14 | — | — | EP | disclosed |
| EP-1593432-A2 | Polymer-supported phosphorus ligands for catalysis | E.I. du Pont de Nemours and Company (US) | 2005-11-09 | — | — | EP | disclosed |
| EP-1593431-A2 | Polymer-supported phosphorus ligands for catalysis | E. I. du Pont de Nemours and Company (US) | 2005-11-09 | — | — | EP | disclosed |
| EP-1593430-A2 | Polymer-Supported phosphorus ligands for catalysts | E.I. DU PONT DE NEMOURS & COMPANY INCORPORATED (US) | 2005-11-09 | — | — | EP | disclosed |
| US-20030228629-A1 | Polymer-supported phosphorus ligands for catalysts | FAGAN PAUL J (US) | 2003-12-11 | — | — | US | disclosed |
| US-6630604-B1 | Phosphine and phosphine oxide ligands are prepared using polymeric supports. These compounds can be easily cleaved from the support, and along with the corresponding supported compounds, used as ligands in the preparation of novel, | E. I. DU PONT DE NEMOURS AND COMPANY | 2003-10-07 | — | — | US | disclosed |
| US-20030104476-A1 | Polymer-supported phosphorus ligands for catalysis | FAGAN PAUL J (US) | 2003-06-05 | — | — | US | disclosed |
| EP-1133357-A2 | POLYMER-SUPPORTED PHOSPHORUS LIGANDS FOR CATALYSIS | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 2001-09-19 | — | — | EP | disclosed |
| WO-2000021663-A2 | POLYMER-SUPPORTED PHOSPHORUS LIGANDS FOR CATALYSIS | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 2000-04-20 | — | — | WO | disclosed |